Do Common Medications Affect the Effectiveness of Gynera Birth Control? - Obstetrics and Gynecology

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Hello, I would like to ask if these medications will affect the contraceptive effectiveness of Gynera?


Hello, my wife is currently using Gynera for contraception, but she has recently caught a cold and is taking the following medications: Panadol, Motilium (active ingredient: Domperidone), Polaramine (active ingredient: Dexchlorpheniramine maleate), Danzen (active ingredient: Serrapeptase), and some vitamins.
I would like to know if these medications will affect the contraceptive effectiveness of Gynera.
Thank you.

Ludwig, 20~29 year old female. Ask Date: 2016/03/27

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, generally it does not have an impact.
Wishing you good health.

Reply Date: 2016/03/27

More Info


When it comes to the effectiveness of birth control pills like Gynera (which contains ethinylestradiol and desogestrel), it is crucial to understand how certain medications can interact with hormonal contraceptives. Your question regarding whether the medications your wife is taking—Panadol (acetaminophen), Motilium (domperidone), Polaramine (dexchlorpheniramine maleate), Danzen (serrapeptase), and various vitamins—will affect the effectiveness of Gynera is very relevant.

Firstly, let's address each medication:
1. Panadol (Acetaminophen): Generally, acetaminophen does not affect the effectiveness of hormonal contraceptives. There is no significant evidence to suggest that it alters the metabolism of estrogen or progestin in birth control pills.

2. Motilium (Domperidone): Domperidone is primarily used to treat nausea and vomiting. It does not have a known interaction with hormonal contraceptives and is not expected to affect the effectiveness of Gynera.

3. Polaramine (Dexchlorpheniramine maleate): This is an antihistamine used for allergy relief. Antihistamines do not interfere with the effectiveness of birth control pills, so your wife can continue taking this medication without concern.

4. Danzen (Serrapeptase): Serrapeptase is an enzyme that is often marketed for its anti-inflammatory properties. There is limited research on its interaction with hormonal contraceptives, but it is generally not known to affect their effectiveness.

5. Vitamins: Most vitamins, including common supplements like vitamin C or vitamin D, do not have any known interactions with birth control pills. However, it is always wise to consult with a healthcare provider regarding any specific supplements, especially herbal ones, as some can interact with hormonal medications.

In summary, the medications your wife is currently taking—Panadol, Motilium, Polaramine, and Danzen—are not known to affect the effectiveness of Gynera. Therefore, she should continue to have reliable contraceptive protection while taking these medications.

However, it is important to note that certain medications, particularly some antibiotics (like rifampicin) and anti-seizure medications (like phenytoin), can reduce the effectiveness of hormonal contraceptives by increasing their metabolism in the liver. This is not the case with the medications listed above.

If your wife has any concerns about her health or the medications she is taking, it is always best to consult with her healthcare provider. They can provide personalized advice based on her medical history and current health status.

Lastly, if she experiences any unusual symptoms or side effects while taking these medications alongside Gynera, she should seek medical advice promptly. It is essential to ensure that she is both healthy and protected against unintended pregnancy.

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