Bilateral Testicular Atrophy in Varicocele Patients - Urology

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Bilateral varicocele?


I have had varicocele for over ten years and have fathered children.
In recent years, I have noticed that my left testicle has shrunk, and there is also a slight change in the right testicle.
There is moderate reflux on the left side, while the right side shows no significant reflux.
Could the reflux from the left varicocele not only harm the left testicle but also affect the right testicle through collateral circulation? Therefore, could the reflux from the left side potentially cause bilateral atrophy, with the left side being more pronounced and the right side being less affected? I am considering undergoing surgery to ligate the left side while leaving the right side untreated.
Will performing unilateral surgery increase the recurrence rate on the left side? Given that there is collateral circulation between both sides, could this lead to the right side affecting the left side's recurrence in the future? Can the microscopic inguinal approach allow for the ligation of the collateral vessels from left to right? Additionally, is there a chance that the surgery could restore testicular volume? Thank you.

aj, 30~39 year old female. Ask Date: 2016/04/05

Dr. Li Xinyi reply Urology


Left-sided varicocele not only harms the left testicle but can also potentially affect the right testicle through collateral circulation.
Currently, there is no clear evidence to support this.
I am considering undergoing surgery to ligate the left side while leaving the right side untreated.
Will performing unilateral surgery increase the recurrence rate on the left side? There is no definitive evidence indicating this.
Microscopic inguinal ligation can theoretically ligate the collateral vessels from the left to the right side.
In principle, this is correct.
Additionally, is there a chance that the surgery could restore testicular volume? It may help, but complete restoration is unlikely.
My recommendation aligns with yours: proceed with microscopic inguinal ligation on the left side first.

Reply Date: 2016/04/05

More Info


Bilateral testicular atrophy in patients with varicocele is a significant concern, particularly for those who have experienced the condition for an extended period. Varicocele, characterized by the enlargement of veins within the scrotum, can lead to various complications, including testicular atrophy, infertility, and hormonal imbalances. In your case, where you have been dealing with varicocele for over a decade and are noticing a reduction in the size of both testicles, it is essential to understand the underlying mechanisms and potential treatment options.

The primary concern with varicocele is the impaired blood flow and increased temperature in the affected testicle, which can lead to damage over time. The left testicle is typically more affected due to anatomical reasons, as the left testicular vein drains into the left renal vein at a right angle, making it more susceptible to increased pressure. This can lead to the left testicle becoming smaller or atrophied, as you have observed. However, the right testicle can also be affected indirectly through collateral circulation, which may explain the slight reduction in size you are noticing on that side as well.

Regarding your question about whether the left-sided reflux can affect the right testicle through collateral pathways, the answer is yes. The venous drainage system of the scrotum is interconnected, and reflux from the left side can potentially impact the right side, albeit to a lesser extent. This is particularly true if there are communicating veins (or collateral pathways) between the two sides, which can facilitate the transfer of pathological conditions from one side to the other.

When considering surgical intervention, such as a varicocelectomy (surgical ligation of the affected veins), it is crucial to weigh the benefits and risks. Performing a unilateral surgery on the left side may indeed lead to a higher recurrence rate if there are significant collateral pathways that could allow for reflux to occur again. However, many surgeons can effectively manage these collateral pathways during surgery, especially if they are aware of their presence.

Regarding your concern about whether a unilateral surgery could lead to future issues on the right side, it is essential to discuss this with your surgeon. They can evaluate the anatomy of your veins and determine the best approach to minimize the risk of recurrence and complications. A microsurgical approach can be beneficial, as it allows for a more precise identification and management of the veins involved, including any communicating veins between the left and right sides.

As for the potential for recovery of testicular volume post-surgery, there is evidence to suggest that surgical intervention can lead to an increase in testicular size, particularly if the atrophy is not severe and if the surgery is performed before significant damage has occurred. The recovery of testicular volume can be influenced by various factors, including the duration of the varicocele, the degree of atrophy, and the overall health of the testicular tissue.

In conclusion, it is advisable to consult with a urologist who specializes in male reproductive health to discuss your specific case in detail. They can provide personalized recommendations based on your condition, including the potential for surgery, the management of collateral pathways, and the likelihood of recovery of testicular volume. Early intervention may help preserve testicular function and improve overall reproductive health.

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