Managing Menstrual Pain with Medications for Tuberous Sclerosis - Pharmacology

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Menstrual pain troubles?


I have been taking medication for epilepsy since I was about eight years old.
Currently, I am taking Lamictal and Keppra.
After a check-up last year, I was diagnosed with tuberous sclerosis.
The main issue is that I experience significant menstrual pain almost every cycle, which requires me to use painkillers.
However, I am currently on neurological medication.
Is it safe for me to take evening primrose oil (to support my uterus and ovaries)?

Xiao Jun, 30~39 year old female. Ask Date: 2016/04/10

Dr. Gu Zhenting reply Pharmacology


Precautions for taking Evening Primrose Oil: Individuals with epilepsy should use caution, as it may lower the seizure threshold and increase the risk of seizures.

Reply Date: 2016/04/10

More Info


Managing menstrual pain can be particularly challenging for individuals with underlying health conditions such as tuberous sclerosis, especially when they are already on medications for epilepsy. Tuberous sclerosis is a genetic disorder that can lead to the growth of benign tumors in various organs, including the brain, kidneys, heart, and lungs. The presence of these tumors can sometimes complicate the management of other health issues, including menstrual pain.

When it comes to managing menstrual pain, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen are commonly recommended. These medications work by reducing inflammation and alleviating pain. However, it is crucial to consult with your healthcare provider before starting any new medication, especially since you are already on antiepileptic drugs like Lamotrigine (樂命錠) and Levetiracetam (優閒). Some medications can interact with each other, potentially leading to increased side effects or reduced effectiveness.

Regarding the use of evening primrose oil (日月見草), it is often taken as a dietary supplement to help with various conditions, including menstrual pain. Evening primrose oil contains gamma-linolenic acid (GLA), which is thought to have anti-inflammatory properties. While it is generally considered safe for most people, it is essential to discuss its use with your healthcare provider, particularly in the context of your existing medications. Your doctor can help determine if it is appropriate for you and monitor for any potential interactions or side effects.

In addition to medications, there are several non-pharmacological approaches to managing menstrual pain that you might consider:
1. Heat Therapy: Applying heat to the lower abdomen can help relax the muscles and alleviate cramping. A heating pad or hot water bottle can be effective.

2. Exercise: Regular physical activity can help reduce the severity of menstrual cramps for some individuals. Gentle exercises like walking, yoga, or stretching can be beneficial.

3. Dietary Changes: Some individuals find relief by making dietary adjustments, such as reducing caffeine and salt intake or increasing omega-3 fatty acids, which may help reduce inflammation.

4. Stress Management: Techniques such as mindfulness, meditation, or deep breathing exercises can help manage stress, which may, in turn, help alleviate menstrual pain.

5. Acupuncture: Some studies suggest that acupuncture may help reduce menstrual pain for some individuals. If you are interested in this option, consult with a qualified practitioner.

6. Consultation with a Specialist: Given your diagnosis of tuberous sclerosis and the complexity of your medication regimen, it may be beneficial to consult with a gynecologist who has experience managing patients with chronic conditions. They can provide tailored advice and treatment options.

In summary, while managing menstrual pain with medications is possible, it is essential to approach this carefully, especially considering your current medications for epilepsy. Always consult with your healthcare provider before starting any new treatment, including over-the-counter medications or supplements like evening primrose oil. They can help you navigate your options safely and effectively, ensuring that your menstrual pain is managed while considering your overall health and existing conditions.

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