Can Thyroid Cancer Patients Take Iodine Supplements After Treatment? - Internal Medicine

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Can patients with thyroid cancer consume iodine-containing dietary supplements?


Dear Dr.
Hsiao,
My mother needs to undergo iodine-131 treatment and a whole-body scan due to papillary thyroid cancer.
After completing the iodine-131 whole-body scan, is it permissible to consume iodine-containing dietary supplements to replenish her strength? If so, is it appropriate to take a supplement that contains 67.5 micrograms of iodine twice a day? Additionally, aside from seaweed, should we also avoid iodine-fortified salt and seafood such as fish and shellfish that grow in seawater?
I appreciate your guidance on these matters.
Thank you.

elaine, 30~39 year old female. Ask Date: 2016/04/12

Dr. Xiao Yongxun reply Internal Medicine


Dear Ms.
Elaine:
1.
Papillary carcinoma is the most common type of malignant thyroid tumor, typically occurring in individuals in their 20s and 30s, as well as in older adults.
It may be associated with prior radiation exposure to the head and neck during childhood.
This type of cancer tends to invade nearby tissues and local lymph nodes, but distant metastasis is less common, and the prognosis is generally favorable.
Clinical manifestations primarily include difficulty swallowing, palpable lumps, voice changes, and shortness of breath.
2.
According to the recommended daily intake of nutrients in our country, the daily iodine intake for women aged 55 to 70 is approximately 80 to 95 micrograms (μg).
3.
To my knowledge, there are no specific recommendations regarding the need for additional iodine supplementation or restrictions on iodine-containing foods and health products for individuals with papillary thyroid carcinoma.
A balanced diet with moderate daily intake is generally advised.
4.
Since not only thyroid diseases but also the use of various medications can affect iodine metabolism, it is recommended that you discuss this matter with your attending physician.

Reply Date: 2016/04/12

More Info


After treatment for thyroid cancer, particularly following radioactive iodine (I-131) therapy, the question of whether patients can take iodine supplements is a nuanced one. The primary concern revolves around the role of iodine in thyroid function and the potential implications for cancer recurrence.

Radioactive iodine therapy is commonly used in the treatment of differentiated thyroid cancers, such as papillary thyroid carcinoma. This treatment works by targeting and destroying any remaining thyroid tissue or cancer cells that may have spread. After undergoing I-131 therapy, patients are often advised to follow a low-iodine diet prior to treatment to enhance the effectiveness of the therapy. This is because high levels of iodine can reduce the uptake of radioactive iodine by thyroid cells, thereby diminishing the treatment's efficacy.

Once the I-131 treatment is completed, the need for iodine supplementation becomes a topic of discussion. In general, the thyroid gland requires iodine to produce thyroid hormones, but after total thyroidectomy and I-131 treatment, the need for iodine may change. Since the thyroid gland has been removed, patients will typically be on thyroid hormone replacement therapy (such as levothyroxine) to maintain normal metabolic function. This medication provides the necessary thyroid hormones without the need for iodine supplementation.

Regarding the specific question about iodine supplements, it is generally advisable for thyroid cancer patients to avoid additional iodine intake from supplements or high-iodine foods immediately after I-131 treatment. This is primarily to prevent any potential interference with the treatment's effects and to avoid stimulating any residual thyroid tissue or cancer cells. The iodine content in supplements, such as the one mentioned (67.5 micrograms), may seem low, but it is essential to consider the cumulative effect of all dietary sources of iodine.

In terms of dietary choices, patients are often advised to limit their intake of iodine-rich foods, especially in the immediate aftermath of I-131 therapy. This includes avoiding seaweed, iodized salt, and certain seafood, which can contribute to higher iodine levels in the body. While it is not necessary to completely eliminate these foods from the diet indefinitely, moderation is key, and patients should consult their healthcare provider for personalized dietary recommendations.

It is also important to note that the long-term management of thyroid cancer involves regular follow-ups, including monitoring thyroglobulin levels and imaging studies, to detect any signs of recurrence. Maintaining a balanced diet that supports overall health is crucial, but specific dietary restrictions should be discussed with an endocrinologist or a healthcare provider familiar with the patient's treatment history.

In conclusion, while iodine is essential for thyroid function, after I-131 treatment and total thyroidectomy, the focus should be on maintaining appropriate thyroid hormone levels through medication rather than iodine supplementation. Patients should consult their healthcare provider before making any changes to their diet or supplement regimen to ensure that their choices align with their treatment plan and overall health goals.

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