Managing Dizziness and Sweating: Insights on Medication Side Effects - Psychiatry

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Consultation for treatment of dizziness and sweating?


Dear Doctor,
My mother, aged 63, has been experiencing issues with autonomic nervous system dysregulation, with prominent symptoms including excessive sweating (sometimes sweating throughout the day) and occasional chest tightness.
She has recently been receiving treatment in a psychosomatic clinic, where the doctor prescribed Purtraline 50 mg (25 mg in the morning and 25 mg in the evening) along with a nutritional supplement.
Initially, she took Purtraline at a dosage of 25 mg/day for three days.
On the first day, she experienced significant dizziness, but this subsided on the following two days.
After her follow-up appointment, the dosage was increased to 50 mg/day (25 mg in the morning and 25 mg in the evening), during which she experienced intermittent dizziness, poor mental state, and fatigue, which are similar to side effects.
When the dosage was reduced back to 25 mg/day, there was an improvement.
I would like to ask the doctor:
1.
Is reducing the dosage a reasonable approach to mitigate side effects?
2.
After stopping the medication for two days, she still experiences mild dizziness every morning.
Could this be a continuation of the side effects? Is there a chance for improvement over time?
Thank you.

Paul, 30~39 year old female. Ask Date: 2016/04/15

Dr. Wu Enliang reply Psychiatry


Hello Paul,
1.
Reducing the dosage is indeed a feasible approach to improve side effects.

2.
Experiencing mild dizziness every morning for two days after discontinuation is likely not a continuation of side effects.
However, it is unclear why the medication was stopped.
Generally, such medications (SSRIs) require some time to show efficacy.
It is advisable to discuss this further with your mother's physician and avoid making any adjustments to the medication on your own.

3.
Additionally, there is no scientific evidence supporting the efficacy of [Cilantro].

Reply Date: 2016/04/15

More Info


Managing dizziness and sweating, particularly in the context of medication side effects, is a crucial aspect of patient care, especially for individuals with autonomic nervous system disorders. In your case, your mother is experiencing symptoms such as excessive sweating and chest tightness, which can be exacerbated by medications like purtraline (a selective serotonin reuptake inhibitor, or SSRI) that are often prescribed for anxiety and depression.

1. Reducing Dosage as a Mitigation Strategy: It is indeed a common and acceptable practice to reduce the dosage of a medication if the patient experiences adverse effects. In your mother’s case, the initial dose of 50 mg/day of purtraline led to dizziness and feelings of fatigue. Reducing the dose back to 25 mg/day, which resulted in symptom improvement, suggests that the higher dose was likely contributing to the side effects. SSRIs can have a range of side effects, including dizziness, fatigue, and gastrointestinal disturbances, particularly when starting treatment or adjusting dosages. Therefore, titrating the dose down is a reasonable approach to manage these side effects while still attempting to achieve therapeutic benefits. It is essential, however, to do this under the guidance of a healthcare provider, as they can monitor for any potential withdrawal symptoms or the return of anxiety or depressive symptoms.

2. Post-Medication Dizziness: The continued experience of lightheadedness two days after stopping purtraline could indeed be related to the medication's lingering effects. SSRIs can have a half-life that varies among individuals, and some may experience withdrawal-like symptoms or a rebound of previous symptoms after discontinuation. The duration of these effects can vary, but they typically resolve within a few days to weeks. It is important to communicate these ongoing symptoms to her healthcare provider, as they may need to consider a more gradual tapering schedule or alternative treatments to minimize withdrawal effects.

In addition to medication management, it may be beneficial to explore non-pharmacological interventions for managing autonomic symptoms. Techniques such as cognitive-behavioral therapy (CBT), mindfulness, and relaxation exercises can help alleviate anxiety and improve overall well-being. Lifestyle modifications, including hydration, dietary adjustments, and regular physical activity, can also support autonomic function and reduce symptoms like sweating and dizziness.

Furthermore, it is crucial to monitor for any other potential causes of dizziness, such as dehydration, electrolyte imbalances, or other underlying medical conditions. A comprehensive evaluation by a healthcare professional can help rule out these factors and ensure that your mother receives the most appropriate care.

In summary, reducing the dosage of purtraline appears to be a valid strategy to manage side effects, and the lightheadedness experienced after stopping the medication may be a temporary issue related to the medication's effects. Continuous communication with her healthcare provider is essential to ensure that her treatment plan is effective and safe.

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