Chronic Nausea: Is Your Sympathetic Nervous System to Blame? - Psychiatry

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Frequent nausea may be suspected to be caused by sympathetic nervous system activity?


Hello, doctor.
I have been experiencing frequent bloating and nausea in my upper abdomen for the past two years.
When it gets severe, it can lead to palpitations and difficulty breathing.
I experience nausea at least a hundred times over a span of seven hours, and the nausea is often intense and loud.
I also suffer from headaches, scalp tingling, and symptoms resembling a stroke.
Sometimes, I have to go to the emergency room.
I have consulted all gastroenterologists and have taken medications for gastroesophageal reflux, prokinetics, and acid suppressants, but none have been effective.
The nausea and bloating persist.
I have also seen a psychiatrist and taken some sedatives, which provide some relief but do not address the root cause.
Eating fruits, sweets, overeating, or being on an empty stomach triggers my gastrointestinal nerves, causing continuous nausea.
I am really at my wit's end.
What could be the underlying issue? Should I see a neurologist? Please respond as soon as possible.
Thank you!

Mr. Chen, 30~39 year old female. Ask Date: 2016/04/21

Dr. Qiu Junda reply Psychiatry


Hello: The letter mentions that you have seen a psychiatrist and that the medication has had some effect, but it does not meet your expectations.
It is recommended that you continue your treatment for a period of time, as some psychological factors affecting physical symptoms (including gastrointestinal issues) cannot be improved in the short term.
During this process, adjustments to the medication may also be necessary, so patience is required.
If you truly wish to switch specialties, please discuss it with your original physician, as they will likely provide appropriate advice.

Reply Date: 2016/04/21

More Info


Chronic nausea can be a debilitating condition, and understanding its potential causes is crucial for effective management. In your case, the symptoms you describe—persistent nausea, abdominal bloating, and associated symptoms like palpitations and difficulty breathing—suggest that there may be a complex interplay between your gastrointestinal system and your nervous system, particularly the sympathetic nervous system.

The sympathetic nervous system is part of the autonomic nervous system, which regulates involuntary bodily functions, including digestion. When the sympathetic nervous system is activated, it can lead to a "fight or flight" response, which may inhibit digestive processes and contribute to symptoms like nausea and bloating. This response can be triggered by stress, anxiety, or other psychological factors, which may explain why you have found some relief with sedatives prescribed by a psychiatrist.

Your history of gastrointestinal issues, including the use of medications for gastroesophageal reflux disease (GERD) and prokinetic agents, indicates that your symptoms may not solely be due to a structural or purely physiological problem. The fact that you have seen multiple gastroenterologists without finding a definitive solution suggests that there may be a functional component to your condition, such as functional dyspepsia or irritable bowel syndrome (IBS), both of which can cause chronic nausea and bloating.

Moreover, the symptoms you experience—such as the exacerbation of nausea after eating certain foods or in specific situations—could indicate a hypersensitivity of the gastrointestinal tract. This hypersensitivity can be influenced by stress and anxiety, which can lead to a cycle of discomfort that exacerbates both your physical and emotional well-being.

Given the complexity of your symptoms, it would be prudent to consider a multidisciplinary approach to your treatment. Here are some recommendations:
1. Neurological Evaluation: Since you mentioned experiencing symptoms like scalp tingling and feelings akin to a stroke, it may be beneficial to consult a neurologist. They can assess whether there are any underlying neurological issues contributing to your symptoms.

2. Psychological Support: Since you have found some relief with sedatives, it may be worth exploring cognitive-behavioral therapy (CBT) or other forms of psychotherapy. These therapies can help address the psychological aspects of chronic nausea and teach coping strategies for managing stress and anxiety.

3. Dietary Modifications: Keeping a food diary may help identify specific triggers for your nausea. Working with a dietitian who specializes in gastrointestinal disorders can provide tailored dietary advice to help manage your symptoms.

4. Alternative Therapies: Some patients find relief through complementary therapies such as acupuncture, mindfulness meditation, or yoga, which can help reduce stress and promote relaxation.

5. Medication Review: A thorough review of your current medications with a healthcare provider may help identify any potential interactions or side effects that could be contributing to your symptoms.

In conclusion, chronic nausea can stem from a variety of factors, including gastrointestinal, neurological, and psychological components. A comprehensive evaluation by a team of specialists, including a gastroenterologist, neurologist, and mental health professional, may provide you with a clearer understanding of your condition and a more effective treatment plan. It’s essential to advocate for yourself and seek the care that addresses all aspects of your health.

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