Fibroadenomas: Diagnosis, Treatment, and Follow-Up Care - Surgery

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Fibroadenoma of the breast


Hello Doctor: At the end of 2015, I had a mammogram that showed microcalcifications (but no clustered calcifications were found).
I then underwent a breast ultrasound, which revealed a calcified mass on the right side.
The doctor advised that monitoring would suffice.
However, I opted for traditional surgery and had one mass removed from each breast, both larger than two centimeters.
The pathology results are as follows: 1.
Right side: Fibroadenoma with sclerosing adenosis and microcalcifications.
Micro: noted focal stromal sclerosis and intraductal epithelial hyperplasia.
2.
Left side: Fibroadenoma with microcalcifications.
Micro: intraductal epithelial hyperplasia.
3.
Immunohistochemical staining was performed: P63 confirmed the presence of myoepithelial cells.
However, after removing one mass from each side, the ultrasound still showed two to three additional masses, approximately 1 cm each, appearing benign.
Therefore, in early April of this year, I went to another hospital for follow-up ultrasound.
Possibly due to the lack of previous medical history for reference, the doctor felt that the masses appeared benign and did not see the need for removal (all about 1 cm, some larger, some smaller), nor did they feel a biopsy was necessary.
-- My questions are: 1.
Does hyperplasia mean proliferation? Could you briefly explain "hyperplasia" and "sclerosing adenosis"? 2.
I am concerned that the masses that were not removed may be hyperplasia or sclerosing adenosis; should I have a biopsy? Is a biopsy under ultrasound preferable, or do you recommend another type? If the biopsy results indicate hyperplasia, should they be removed? 3.
Does performing automated breast volume scanning (ABVS) truly allow for tracking changes in data? Can it better capture symptoms? 4.
What do you recommend for follow-up? Is "image-guided minimally invasive breast tumor surgery" preferable? (I worry that if there is hyperplasia, it may not be completely removed with minimally invasive techniques) or is traditional surgery more beneficial for interpreting biopsy results? (Yet I feel there are a few masses) Thank you for taking the time to read my lengthy message, and I wish you and your family peace and safety.

Sincere, 30~39 year old female. Ask Date: 2016/04/21

Dr. Li Zhonghuai reply Surgery


Hello! It is recommended to follow up with the same physician and not to visit multiple hospitals.
Sclerosing adenosis requires long-term monitoring, as international journal studies have shown that it increases the likelihood of in situ carcinoma.
Regardless of the type of biopsy performed, it is advisable to have follow-ups at least every six months.
Regarding benign tumors, you may consider whether it is worth removing them if it causes a depression in the breast's appearance.
Take care! Changhua Hospital cares about you!

Reply Date: 2016/04/21

More Info


Understanding fibroadenomas, particularly in the context of breast health, is crucial for managing and monitoring breast conditions. Fibroadenomas are benign tumors composed of glandular and stromal (connective) tissue, commonly found in women, especially those in their reproductive years. They are often discovered through imaging studies such as mammograms or ultrasounds, and they can present as palpable lumps in the breast.


1. Understanding Hyperplasia and Sclerosing Adenosis
Hyperplasia refers to an increase in the number of cells in a tissue or organ, which can lead to its enlargement. In the context of breast tissue, "intraductal epithelial hyperplasia" indicates an increase in the number of cells lining the ducts of the breast, which is often considered a benign condition but can sometimes be associated with an increased risk of breast cancer.

Sclerosing adenosis, on the other hand, is a condition characterized by the proliferation of glandular tissue along with fibrosis (scarring). This condition can also present with calcifications on mammograms and is generally benign. However, it may complicate the interpretation of mammograms due to the presence of calcifications that can mimic malignancy.


2. Concerns About Remaining Lesions
Given that you have several remaining lesions that are approximately 1 cm in size, it is understandable to be concerned about their nature. While the previous pathology reports indicate benign conditions, the presence of hyperplasia or sclerosing adenosis in the context of fibroadenomas does warrant careful monitoring.
If the ultrasound shows changes in these lesions, or if they grow, a biopsy may be indicated to rule out any atypical or malignant changes. The choice of biopsy method can depend on various factors, including the size and location of the lesions. Core needle biopsy is often preferred for its accuracy and minimal invasiveness, while excisional biopsy (surgical removal) may be considered if there is significant concern about the nature of the lesions.


3. Role of Automated Breast Volume Scanner (ABVS)
Automated Breast Volume Scanner (ABVS) is a relatively newer imaging modality that provides a three-dimensional view of the breast. It can be beneficial for monitoring changes in breast lesions over time. While it may not replace traditional imaging methods like mammography or ultrasound, it can complement them by providing additional data on the size and characteristics of breast lesions. However, it is essential to discuss with your healthcare provider whether ABVS is appropriate for your specific situation.


4. Recommendations for Follow-Up and Management
For follow-up care, regular monitoring through imaging studies is essential. Depending on the characteristics of the lesions and any changes observed, your healthcare provider may recommend follow-up ultrasounds every 6 to 12 months. If there are any significant changes, such as an increase in size or changes in appearance, further evaluation, including a biopsy, may be warranted.

Regarding the choice between minimally invasive procedures and traditional surgery, it is crucial to weigh the risks and benefits. Minimally invasive techniques can be effective for removing small, well-defined lesions, but if there is a concern about the presence of hyperplasia or other changes, a more extensive surgical approach may be necessary to ensure complete removal and accurate pathology assessment.

In conclusion, while fibroadenomas are generally benign, the presence of hyperplasia and sclerosing adenosis necessitates careful monitoring and possibly further evaluation. Regular follow-ups with your healthcare provider, imaging studies, and discussions about the best approach for any remaining lesions will help ensure your breast health is managed appropriately. Always feel free to ask your healthcare provider any questions or express concerns about your treatment plan. Your proactive approach to your health is commendable, and staying informed is key to making the best decisions for your care.

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