Can Diabetes Medication Affect Fertility in Men? - Internal Medicine

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Diabetic patients


I already have a child who is currently 3 years and 7 months old.
I have been wanting to have another child, but I later found out that my husband is taking medication for diabetes.
Could this be a reason why it is more difficult to conceive? Thank you for your response.

Qiu Bi Te, 40~49 year old female. Ask Date: 2016/05/04

Dr. Xiao Yongxun reply Internal Medicine


Dear Miss Cupid:
1.
Infertility is defined as a couple's inability to conceive after one year of regular, unprotected intercourse.
Approximately 40% of infertility cases are attributed to male factors, 20% to female hormonal issues, 30% to female pelvic factors, 5% to an unsuitable cervical environment, and the remaining 5% are of unknown origin.
In women, the incidence of infertility is related to age, with the rate being twice as high for those aged 35 to 44 compared to those aged 30 to 34.
Epidemiological studies show that the likelihood of pregnancy significantly decreases for women over the age of 36; you may have heard this from your obstetrician-gynecologist.
It is indeed fortunate yet challenging to conceive and give birth at around the age of 42.
2.
Complications of diabetes include sexual dysfunction, erectile difficulties, and other related issues; these problems may be more pronounced than the side effects of diabetes medications.
In terms of male infertility, factors such as diabetes, smoking, age, various diseases, and toxins can all affect sperm count, quality, and motility.
While it is impossible to completely rule out the impact of diabetes medications on male reproductive capacity, clinical experience and research reports indicate that there is little evidence of diabetes medications affecting fertility.
Conversely, there are numerous reports and studies linking poor blood sugar control to sexual dysfunction.
3.
Given the advancements and specialization in reproductive medicine, I kindly suggest that you first discuss your concerns with your primary care physician or directly consult with a gynecologist or urologist to avoid any delays in treatment.

Reply Date: 2016/05/04

More Info


Diabetes can indeed have an impact on fertility, particularly in men, but the relationship is complex and influenced by various factors. When considering the effects of diabetes medication on male fertility, it is essential to understand both the condition itself and the medications used to manage it.

Firstly, diabetes can lead to several complications that may affect fertility. For men, one of the most significant issues is erectile dysfunction, which is more prevalent in those with poorly controlled diabetes. High blood sugar levels can damage blood vessels and nerves, leading to difficulties in achieving or maintaining an erection. This can directly impact the ability to conceive, as sexual function is crucial for natural conception.

Regarding diabetes medications, the evidence suggests that most commonly prescribed diabetes medications do not significantly impair male fertility. For instance, medications like metformin and insulin, which are frequently used to manage diabetes, have not been shown to have a detrimental effect on sperm quality or overall fertility. However, it is essential to note that uncontrolled diabetes, characterized by high blood sugar levels, is more likely to contribute to fertility issues than the medications themselves.

In your case, since your husband is on diabetes medication, it is crucial to ensure that his blood sugar levels are well-managed. Good glycemic control can mitigate many of the complications associated with diabetes, including those affecting sexual health and fertility. If your husband is experiencing any side effects from his medication or has concerns about his fertility, it would be beneficial for him to discuss these with his healthcare provider. They can assess his overall health, review his medication regimen, and make any necessary adjustments.

Additionally, other lifestyle factors can also play a significant role in male fertility. Maintaining a healthy weight, engaging in regular physical activity, avoiding smoking, and limiting alcohol consumption can all contribute to improved fertility outcomes. Stress management is also vital, as psychological factors can influence both sexual function and fertility.

If you and your husband are actively trying to conceive, it may also be helpful to consult with a fertility specialist. They can conduct a thorough evaluation of both partners' reproductive health and provide tailored advice and treatment options. This could include lifestyle modifications, fertility testing, or assisted reproductive technologies if necessary.

In summary, while diabetes and its medications can influence fertility, the primary concern lies in the management of the condition itself. Ensuring that blood sugar levels are stable and addressing any complications related to diabetes will be key to improving your chances of conceiving. Open communication with healthcare providers and a focus on overall health will support your family planning efforts.

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