Pregnancy Testing: Delayed Period Concerns and Results - Obstetrics and Gynecology

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I would like to inquire about pregnancy testing questions?


Hello Doctor: My menstrual cycle has always been regular (almost exactly 28 days), but starting in April, I experienced a delay (I was supposed to start on April 2, but it was delayed until April 4).
I had sexual intercourse on April 23, using a condom the entire time and confirming that there were no breaks.
My period should have started on May 1 (counting from April 4), but as of May 5, it has not appeared, resulting in a 5-day delay.
I was quite worried, so I took a pregnancy test on the morning of May 3, which came back negative.
I also visited a gynecologist, and the pregnancy test there was also negative.
An internal ultrasound was performed as well.
On the mornings of May 4 and May 5, I took another pregnancy test, which again was negative.
Based on this situation, what is the likelihood of being pregnant? Thank you, Doctor! P.S.
I had been taking antibiotics and anti-inflammatory medication continuously for over a month from mid-February to the end of March due to other health issues.
Could this have affected my menstrual cycle? Thank you, Doctor!

Niming, 20~29 year old female. Ask Date: 2016/05/05

Dr. Tian Yiwen reply Obstetrics and Gynecology


If conception occurs during sexual intercourse, the earliest a pregnancy test can detect pregnancy is two weeks after the act.
A woman's menstrual cycle can be easily affected by stress or lifestyle factors, so it is recommended to wait and see.
If menstruation does not occur after two weeks past the expected date, then a pregnancy test can be taken.
If the test is negative and menstruation has not occurred for over two months, it is advisable to consult a gynecologist.
Some individuals may find that their period arrives during the waiting period.

Additionally, it is important to promote that if sexual activity is frequent, women should consider long-term use of oral contraceptives (which provide the best contraceptive effect) along with the male partner using condoms (to prevent sexually transmitted infections).
This protects both partners.
Relying on methods such as calculating safe periods, withdrawal (pull-out method), or using condoms alone are not appropriate contraceptive measures.
By practicing effective contraception beforehand, there is no need to feel anxious after each sexual encounter.

Reply Date: 2016/05/05

More Info


When it comes to understanding delayed periods and the implications for pregnancy testing, it's essential to consider several factors that can influence menstrual cycles and the accuracy of pregnancy tests. Based on your description, it seems you have a regular menstrual cycle, typically around 28 days, but have recently experienced some delays.
Firstly, let's address the possibility of pregnancy. You mentioned that you had unprotected intercourse on April 23, and your expected period was on May 1, but it was delayed until May 5. You performed multiple pregnancy tests, all of which returned negative results. Given that you used condoms during intercourse and confirmed there were no breakages, the likelihood of pregnancy is quite low. Condoms are generally effective in preventing pregnancy when used correctly, and the negative pregnancy tests further support this conclusion.

However, it's important to note that pregnancy tests are most accurate when taken after a missed period. Testing too early can lead to false negatives, especially if the hormone hCG (human chorionic gonadotropin) has not yet reached detectable levels in your urine. Since you tested on May 3 and your period was due on May 1, it might have been a bit early, but given that you continued to test negative even after your expected period, it is unlikely that you are pregnant.

Regarding your concern about the impact of antibiotics and anti-inflammatory medications on your menstrual cycle, it is indeed possible for certain medications to affect your cycle. While antibiotics are not typically known to cause significant menstrual irregularities, they can influence the gut microbiome and overall health, which in turn may affect hormonal balance. Anti-inflammatory medications can also have an impact on your cycle, particularly if they are used frequently or in high doses. Stress, changes in weight, and lifestyle factors such as sleep patterns can also contribute to menstrual irregularities.

In your case, since you have experienced a delay of five days, it might be beneficial to consider other factors that could be influencing your cycle. Stress, changes in routine, or even minor illnesses can lead to temporary disruptions. If your period does not arrive soon, or if you continue to experience unusual symptoms, it would be wise to consult with a healthcare provider for further evaluation. They may recommend additional tests or assessments to rule out any underlying conditions that could be affecting your menstrual cycle.

In summary, based on the information provided, the likelihood of pregnancy appears low given the use of condoms and the negative pregnancy tests. However, if your period does not arrive soon or if you have further concerns, seeking medical advice would be the best course of action. It's essential to monitor your body and any changes closely, as they can provide valuable insights into your reproductive health.

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