Could Severe Ulcers Found During Colonoscopy Indicate Colon Cancer? - Gastroenterology and Hepatology

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A colonoscopy revealed severe ulceration at 40 centimeters. Could this be colon cancer?


Hello Doctor: My wife is currently 35 years old.
Last June, during a colonoscopy at Taipei Medical University, a 0.2 cm hyperplastic polyp was found 15 cm from the anus, and no other abnormalities were noted.
The biopsy results were benign.
However, during this year's health check, another colonoscopy was performed, but the doctor could only examine 40 cm before stopping due to severe ulcerative bleeding and recommended that we seek outpatient evaluation.
I would like to ask if there is a possibility that this could be colon cancer, especially since she had a normal result just last year.
My wife has been under significant work stress for the past two months; could this be related? P.S.
The gastroscopy results were normal.
Thank you.

Protonzz, 30~39 year old female. Ask Date: 2016/05/17

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: The appearance of ulcerative colitis and colorectal cancer differs under endoscopy.
It is recommended to consult a gastroenterologist and arrange for endoscopic follow-up.
If necessary, a biopsy can be performed to distinguish between inflammation and colorectal cancer.
Changhua Hospital cares about your health.
Dr.
Tsai An-Shun.

Reply Date: 2016/05/17

More Info


Severe ulcers found during a colonoscopy can indeed raise concerns about the possibility of colon cancer, but they do not automatically indicate cancer. In your wife's case, the presence of a previously identified benign polyp and the recent discovery of severe ulcers warrant further investigation to determine the underlying cause of the ulcers.

Colon cancer can develop from pre-existing polyps, particularly adenomatous polyps, which have the potential to become malignant over time. However, not all polyps are cancerous, and many are benign, as was the case with your wife's previous polyp. The fact that her polyp was classified as hyperplastic suggests that it is less likely to progress to cancer compared to adenomatous polyps.
The severe ulcers observed during the recent colonoscopy could be due to various factors, including inflammatory bowel disease (IBD), infections, or even ischemic colitis, especially if there is a history of stress or other health issues. Stress can exacerbate gastrointestinal symptoms and may contribute to conditions like IBD, but it is not a direct cause of cancer.
Given that the doctor was unable to continue the colonoscopy due to the severity of the ulcers, it is crucial to follow up with a gastroenterologist for a thorough evaluation. This may include additional imaging studies, laboratory tests, or even a repeat colonoscopy to obtain biopsies from the ulcerated areas. Biopsies are essential for determining whether the ulcers are related to cancer or another condition, such as chronic inflammation or infection.

In terms of timing, it is not uncommon for significant changes to occur in the colon within a year, especially if there are underlying risk factors such as family history, personal history of polyps, or symptoms suggestive of bowel disease. Regular screening and monitoring are vital, particularly for individuals with risk factors for colorectal cancer.

In summary, while severe ulcers can be a cause for concern regarding colon cancer, they are not definitive proof of malignancy. It is essential to conduct further investigations to clarify the diagnosis and determine the appropriate course of action. Your wife's healthcare provider will be able to guide you on the next steps, which may include additional colonoscopies, imaging studies, or other diagnostic procedures. Early detection and intervention are key in managing any potential issues effectively.

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