Missed Progesterone: Could It Affect My Period After Ovulation? - Obstetrics and Gynecology

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It has been 21 days since the trigger shot, and my menstrual cycle has not started yet?


Hello Doctor: I received an ovulation trigger shot on April 28, had intercourse on April 29 and 30, and started taking progesterone on April 30.
However, I have been quite busy this month and forgot to take the progesterone, possibly taking less than half of the prescribed amount, and I still have a lot of medication left...
@@ I haven't tested for pregnancy this month.
Doctor, will not taking the progesterone on time have an impact? Can I finish the medication now? In my last treatment, I took progesterone for 14 days after the ovulation trigger shot, and my period came exactly three days after stopping the medication.
It has now been 21 days since this treatment; is there a possibility of pregnancy? Thank you, Doctor.

Lai Xiaojie, 30~39 year old female. Ask Date: 2016/05/19

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, you can finish taking the medication.
If you might be pregnant and still haven't gotten your period by next Monday, it is recommended to see a gynecologist.
Wishing you good health.

Reply Date: 2016/05/19

More Info


When it comes to missed doses of progesterone, particularly in the context of ovulation and menstrual cycles, there are several important factors to consider. Progesterone is a hormone that plays a crucial role in regulating the menstrual cycle and maintaining pregnancy. It is typically prescribed after ovulation to support the uterine lining and prepare it for a potential pregnancy.
In your case, you mentioned that you received an ovulation trigger shot on April 28 and began taking progesterone on April 30. However, due to a busy schedule, you have not been consistent with your progesterone intake, taking it only intermittently. This inconsistency can indeed affect your menstrual cycle and the likelihood of pregnancy.

1. Impact of Missed Doses: Missing doses of progesterone can lead to insufficient levels of the hormone in your system. If progesterone levels are too low, it may not adequately support the uterine lining, which can result in a shorter luteal phase (the time between ovulation and the start of your period). This could lead to an earlier onset of menstruation or, conversely, if you are pregnant, it may increase the risk of miscarriage due to inadequate hormonal support.

2. Continuing the Medication: It is generally advisable to complete the course of medication as prescribed, even if you have missed doses. However, the effectiveness of the remaining doses may be diminished due to the previous missed doses. If you have not taken the medication consistently, it may not provide the intended support for your menstrual cycle or potential pregnancy.
3. Pregnancy Testing: Since you have not yet taken a pregnancy test, it would be prudent to do so, especially since you have passed the typical time frame for your period to start. If you are pregnant, the presence of progesterone is crucial for maintaining the pregnancy, and you should consult your healthcare provider for guidance on how to proceed with the medication.

4. Timing of Your Period: You mentioned that your period usually arrives three days after stopping progesterone. Given that you have not taken the medication consistently this month, it is difficult to predict when your period will arrive. If you have not taken enough progesterone to support the luteal phase, your period may come sooner than expected.

5. Consulting a Healthcare Provider: Given the complexities of hormone therapy and the potential implications for your menstrual cycle and pregnancy, it is essential to consult with your healthcare provider. They can provide personalized advice based on your specific situation, including whether to continue taking the remaining progesterone and when to take a pregnancy test.

In summary, missed doses of progesterone can affect your menstrual cycle and the likelihood of pregnancy. It is important to complete the medication if possible, but also to consult with your healthcare provider for tailored advice. Taking a pregnancy test will help clarify your situation, and your provider can guide you on the next steps based on the results.

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