Medication Side Effects: Can You Safely Combine Sleep Aids? - Pharmacology

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Adverse drug effects


Hello, pharmacist.
I would like to ask about the medication for my neurological condition that I picked up today.
I spoke with my doctor and mentioned that my stress levels haven't increased recently.
I requested a milder medication for insomnia, but the doctor prescribed the same medication I was already taking, which is Eslonopram 0.25 mg.
I used to take it in the morning, but now I need to take it after breakfast and before bed.
I apologize for not taking the medication regularly, as I researched its side effects online, which seem quite concerning.
I would like to ask if this medication can be taken long-term, as I read it might cause memory impairment.
Additionally, I am currently taking a heart medication, Amlodipine Extended-Release Tablet 60 mg.
Can I take it together with Eslonopram 0.25 mg? Lastly, I tend to have racing thoughts before sleep; is it okay if I take half of the medication instead?

Cai Xiansheng, 30~39 year old female. Ask Date: 2016/05/23

Dr. Hou Fangmin reply Pharmacology


Hello Mr.
Tsai:
1.
There are no interactions between Apixaban extended-release film-coated tablets and Lurasidone 0.25 mg.

2.
The function of Lurasidone is to rapidly alleviate anxiety, providing sedation, sleep aid, and anti-anxiety effects.
This medication is considered a mild sedative with minimal side effects; taking half a dose before bedtime is also acceptable.
It is also used for gastric ulcers and can be helpful for racing thoughts.
I see that you are quite anxious, but following your physician's instructions should be fine.
Now that your health insurance card is registered, your physician can view the medications you are taking through the health insurance cloud system, so please adhere to your doctor's guidance.
Lastly, I wish you peace and good health.

Reply Date: 2016/05/23

More Info


Combining sleep aids and other medications can be a complex issue, especially when considering potential side effects and drug interactions. In your case, you mentioned taking a sleep aid called "癒利舒盼錠" (which I assume is a form of a benzodiazepine or similar medication) at a lower dose of 0.25 mg, and you are also on heart medication, specifically "愛彼脈持續性效膜衣錠" (likely a beta-blocker or similar).

Understanding the Medications
1. 癒利舒盼錠 (Sleep Aid): This medication is likely a benzodiazepine or a similar sedative. Benzodiazepines can be effective for short-term management of insomnia, but they come with potential side effects, including drowsiness, dizziness, and in some cases, memory impairment, especially with long-term use. The risk of dependence also increases with prolonged use.

2. 愛彼脈持續性效膜衣錠 (Heart Medication): Depending on the specific medication, it may have its own set of side effects and interactions. For example, if it is a beta-blocker, it can help manage heart rate and blood pressure but may also cause fatigue or dizziness.


Combining Medications
When considering whether you can safely combine these medications, it is essential to evaluate:
- Potential Interactions: Generally, combining a sleep aid with heart medication can be safe, but it depends on the specific drugs involved. Benzodiazepines can enhance the sedative effects of other medications, which may lead to increased drowsiness or dizziness.
- Dosage Adjustments: If you feel that the full dose of your sleep aid is too strong, it is crucial to consult with your healthcare provider before making any changes. Some individuals may benefit from a lower dose, but this should be done under medical supervision to ensure safety and efficacy.


Long-term Use and Side Effects
Regarding the long-term use of your sleep aid, it is generally not recommended to use benzodiazepines for extended periods due to the risk of tolerance, dependence, and cognitive effects, such as memory impairment. If you are experiencing significant stress and insomnia, it may be beneficial to explore other treatment options, such as cognitive-behavioral therapy for insomnia (CBT-I), which can provide long-term benefits without the risks associated with medication.


Recommendations
1. Consult Your Healthcare Provider: Before making any changes to your medication regimen, including adjusting dosages or combining medications, it is essential to discuss your concerns with your doctor or pharmacist. They can provide personalized advice based on your medical history and current medications.

2. Monitor Side Effects: Keep track of any side effects you experience while taking these medications. If you notice increased drowsiness, memory issues, or any other concerning symptoms, report these to your healthcare provider.

3. Consider Non-Pharmacological Approaches: In addition to medication, consider incorporating lifestyle changes that can improve sleep quality, such as establishing a regular sleep schedule, practicing relaxation techniques, and creating a conducive sleep environment.

4. Regular Follow-ups: Schedule regular follow-ups with your healthcare provider to reassess your treatment plan, especially if your stress levels or sleep patterns change.

In summary, while combining sleep aids with heart medications can be safe, it is essential to approach this carefully and under the guidance of a healthcare professional. Always prioritize open communication with your healthcare team to ensure the best outcomes for your health and well-being.

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