Ovarian Health: Concerns About Hormonal Treatments and Fertility - Obstetrics and Gynecology

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I have not grown taller and did not experience puberty until I was around 23 or 24 years old.
After receiving growth hormone injections, my breasts developed a little, and I started menstruating naturally every two to three months.
When I went for a follow-up appointment with a pediatric endocrinologist, the doctor prescribed two medications, which allowed me to have regular periods while taking them, but my periods stopped again when I was not on the medication.
In my thirties, I consulted a doctor and underwent an endoscopy.
The doctor mentioned that I have ovarian calcification and that my uterus has not developed much.
I was prescribed Duoluton, which also resulted in regular periods while I was taking it, but I had no issues when I stopped.
I am concerned about the long-term side effects of taking Duoluton.
When I went to the pharmacy to buy it, I was told it has been discontinued.
The doctor also mentioned that if I want to have children, I might need to consider egg donation.
What is the feasibility of that? Additionally, if I want to seek medical advice, which type of doctor should I consult for my condition? I have been off Duoluton for a year now, and since stopping, I often feel like there is something in my throat.
I saw an ENT specialist who found no foreign body.
I am unsure if this sensation is a side effect.

tina, 30~39 year old female. Ask Date: 2002/09/08

Dr. Zhan Deqin reply Obstetrics and Gynecology


1.
Dufaston contains estrogen and progesterone, which are hormones.
There are many similar products available, and given your situation, there isn't a better option.
An annual breast ultrasound should suffice.
2.
Egg donation for conception is currently quite popular and should be feasible.
3.
Consult with an endocrinologist specializing in reproductive health.
4.
It should not be related to Dufaston.

Reply Date: 2002/09/08

More Info


Understanding ovarian health and the implications of hormonal treatments on fertility is a complex issue that requires careful consideration of various factors, including individual medical history, hormonal balance, and the specific medications involved.

Firstly, it is important to address your concerns regarding the long-term use of Duoluton (a combination of hormones typically used for hormone replacement therapy). While hormonal treatments can be effective in managing symptoms related to ovarian dysfunction, they may also carry potential side effects. Common side effects of long-term hormonal therapy can include weight gain, mood swings, headaches, and an increased risk of blood clots. It is crucial to have regular follow-ups with your healthcare provider to monitor any adverse effects and to evaluate the ongoing need for such treatment.

Regarding your concern about ovarian calcification and the potential need for egg donation to conceive, it is essential to understand that ovarian health can significantly impact fertility. Ovarian calcification may indicate underlying issues with ovarian function, which could affect the quality and quantity of eggs produced. If your doctor has suggested the possibility of using donor eggs, this is often considered when there are significant concerns about the viability of your own eggs. The success rates of using donor eggs are generally high, especially for women who may have difficulty conceiving with their own eggs due to age or ovarian health issues.

If you are considering fertility treatments, it is advisable to consult with a reproductive endocrinologist or a fertility specialist. These professionals specialize in diagnosing and treating reproductive health issues and can provide tailored advice based on your specific situation. They can also guide you through the process of egg donation, if necessary, and discuss the associated risks and benefits.

As for the symptoms you are experiencing after stopping Duoluton, such as the sensation of a foreign body in your throat, it is essential to communicate these concerns to your healthcare provider. While it may not be directly related to the medication, any persistent symptoms should be evaluated to rule out other underlying conditions. It is also worth noting that hormonal fluctuations after discontinuing treatment can lead to various physical sensations and symptoms, which may take time to stabilize.

In summary, navigating ovarian health and fertility concerns requires a comprehensive approach. Regular consultations with a knowledgeable healthcare provider, particularly a reproductive endocrinologist, can help you understand your options, manage any side effects of hormonal treatments, and explore the feasibility of conception, whether through natural means or assisted reproductive technologies. It is crucial to stay informed and proactive about your health, ensuring that you receive the best possible care tailored to your unique circumstances.

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