Glaucoma Risks: Insights from Eye Exam Results - Ophthalmology

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Questions about glaucoma?


Hello doctor, I went for an examination, and the OCT results are normal, with intraocular pressure between 19-20 mmHg, visual fields normal, but the optic cup-to-disc ratio is relatively large, approximately 0.7.
I would like to ask if a physiological optic cup can be as large as 0.7-0.8? Will I be at higher risk for glaucoma in the future? During the OCT examination, the report showed that the TSNIT graph indicates most areas are in the green range, but a small portion is significantly above the green range.
What does this mean? Does it indicate that my eyes are healthy, or could it be due to excessive lutein supplementation? The doctor mentioned that as long as I don't fall into the red zone, I can be at ease, but since it is so much higher than the green range, I still feel uneasy.
Lastly, I would like to ask if it is normal for my two eyes to have different brightness levels.
Thank you for your response!

Mao Mao, 20~29 year old female. Ask Date: 2016/05/31

Dr. He Jianxian reply Ophthalmology


The physiological cup-to-disc ratio can range from 0.7 to 0.8, and there is no correlation with the future development of glaucoma.
If intraocular pressure and visual fields are normal, there is no need for excessive concern.

Reply Date: 2016/05/31

More Info


Hello! Thank you for your detailed inquiry regarding your eye health and concerns about glaucoma risks. Based on the information you've provided, let's break down your questions and address them one by one.

1. Physiological Cup Size: A cup-to-disc ratio of 0.7 is indeed within the range of normal physiological variations, although it is on the higher end. The optic nerve head (where the optic nerve exits the eye) can naturally vary in size among individuals. A cup-to-disc ratio of 0.7 does not automatically indicate glaucoma, especially if your other tests (OCT, intraocular pressure, and visual field) are normal. However, it is essential to monitor this ratio over time, as changes can indicate potential issues.

2. Risk of Developing Glaucoma: Your intraocular pressure (IOP) readings of 19-20 mmHg are considered borderline. While normal IOP is typically below 21 mmHg, glaucoma can occur even at normal pressures (this is known as normal-tension glaucoma). The presence of a larger cup-to-disc ratio, especially in conjunction with other risk factors (like family history, age, and ethnicity), may increase your risk. Regular follow-ups with your eye care professional are crucial to monitor any changes.

3. OCT Results and TSNIT Graph: The TSNIT (Temporal-Superior-Nasal-Inferior-Temporal) graph is a useful tool in assessing the thickness of the retinal nerve fiber layer. If most of your readings are in the green zone, this is generally a good sign, indicating that your nerve fiber layer is healthy. However, if a small portion is above the green range, it could suggest localized thickening or a variation that may need further investigation. It does not necessarily indicate that you are over-supplementing with lutein; rather, it might reflect individual anatomical differences or variations in nerve fiber layer thickness. Your doctor’s reassurance that you should not fall into the red zone is sound advice, but it’s essential to keep an eye on any changes in your readings.

4. Differences in Brightness Between Eyes: Experiencing different brightness levels between your eyes can be normal, especially if there are slight differences in refractive error or if one eye is more sensitive to light than the other. However, if this difference is significant or accompanied by other symptoms (like sudden vision changes, pain, or flashes of light), it would be wise to consult your eye care provider for further evaluation.

In summary, while your current test results appear stable, it is essential to maintain regular check-ups to monitor your eye health, especially given the larger cup-to-disc ratio. Keeping track of any changes in your vision or eye comfort is crucial. If you have any further concerns or if you notice any new symptoms, do not hesitate to reach out to your eye care professional. They can provide personalized advice and reassurance based on your specific situation. Remember, proactive eye care is key to maintaining good vision health!

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