Radiation therapy issues
Dr.
Chen: Hello! I have two questions I would like to ask you, thank you! 1/ After a lumpectomy for stage II breast cancer, is it possible to choose not to undergo chemotherapy? Since the lymph nodes are clear, the doctor mentioned that I could opt for radiation therapy and continuous medication for ten years.
2/ The surgery has already been completed, but due to a high volume of patients, my radiation therapy has been scheduled for six months later.
Will delaying radiation therapy for six months affect the treatment's effectiveness or increase the risk of recurrence? Thank you, Dr.
Chen, for answering my questions; I truly appreciate it! Ms.
Li
Ms. Li, 50~59 year old female. Ask Date: 2016/05/31
Dr. Chen Sirong reply Oncology
Ms.
Li / 54 years old / Female
1/ Can a patient with stage II breast cancer choose not to undergo chemotherapy after a lumpectomy? Since the lymph nodes are clear, the doctor mentioned that radiation therapy and continuous medication for ten years are options.
A: It's difficult to assess without knowing the specific type of cancer cells.
If it is invasive ductal carcinoma stage II, we typically recommend chemotherapy.
The surgery has been completed, but due to a high volume of patients, my radiation therapy has been scheduled for six months later.
Will delaying radiation therapy for six months affect the treatment's effectiveness or increase the risk of recurrence?
A: If chemotherapy is administered, radiation therapy should ideally start 3-4 weeks after the last chemotherapy session.
If radiation therapy is to be given directly after surgery, it is best to initiate it within 4-6 weeks post-surgery.
Thank you, Taoyuan Hospital, Dr.
Chen Sih-Rong.
Reply Date: 2016/05/31
More Info
Dear Ms. Li,
Thank you for your questions regarding the management of Stage II breast cancer following surgery. It’s important to address your concerns thoroughly, as the decisions made during this phase of treatment can significantly impact your prognosis and overall health.
1. Can you choose not to undergo chemotherapy after local excision for Stage II breast cancer?
Yes, it is possible to forgo chemotherapy after surgery for Stage II breast cancer, especially if your lymph nodes are clear of cancer. The decision to use chemotherapy often depends on several factors, including the tumor's characteristics (such as hormone receptor status and HER2 status), the size of the tumor, and the overall health of the patient. In your case, if your oncologist has indicated that radiation therapy and a ten-year course of hormone therapy (like an aromatase inhibitor or tamoxifen) are sufficient, this may be a reasonable approach.
Radiation therapy is typically recommended after breast-conserving surgery (lumpectomy) to reduce the risk of local recurrence. Hormone therapy can further decrease the risk of recurrence, particularly in hormone receptor-positive cancers. However, it’s essential to have a detailed discussion with your oncologist about the potential benefits and risks of omitting chemotherapy, as well as the specific characteristics of your tumor that may influence this decision.
2. Will delaying radiation therapy for six months affect treatment outcomes or increase the risk of recurrence?
Delaying radiation therapy after surgery can raise concerns about the potential for cancer recurrence. Generally, the sooner radiation therapy is initiated after surgery, the better, as it helps to eliminate any remaining cancer cells in the breast and surrounding tissues. However, the exact impact of a six-month delay can vary based on individual circumstances, including the biology of the tumor and the overall treatment plan.
Research indicates that delays in starting adjuvant radiation therapy can be associated with a slightly increased risk of local recurrence, particularly in patients with higher-risk features. However, the degree of risk can depend on various factors, including tumor size, grade, and hormone receptor status. In your case, if your oncologist has assessed that the delay is manageable given your specific situation, it may be acceptable.
It’s crucial to maintain open communication with your healthcare team. If you have concerns about the timing of your radiation therapy, I encourage you to discuss them with your oncologist. They can provide insights based on the latest research and your unique clinical scenario.
In summary, while it is possible to forgo chemotherapy in certain cases of Stage II breast cancer, the decision should be made collaboratively with your healthcare team, considering all aspects of your diagnosis and treatment plan. Additionally, while a delay in radiation therapy can raise concerns about recurrence, your oncologist will be best positioned to assess the risks and benefits in your specific case.
Thank you for reaching out with your questions, and I wish you the best in your treatment journey.
Warm regards,
Dr. Chen
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