Infertility: Key Questions and Concerns for Couples - Obstetrics and Gynecology

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Regarding infertility?


Hello Dr.
Wu, I have been married for over two years and have not used contraception for more than a year, but I have not become pregnant.
I was pregnant shortly after getting married, but I did not carry the pregnancy to term due to my studies.
After terminating the pregnancy, I started using contraception, and I have not used it since June of last year, but I still have not become pregnant.
Under the guidance of a gynecologist, I took ovulation medication for six months, but it was unsuccessful.

(1) What kind of tests should I undergo? I am concerned that the previous pregnancy may not have been completely terminated.

(2) My menstrual cycle is irregular; sometimes it is 28 days, and other times it is 35 days.
Could this be affecting my ability to conceive?
(3) I work night shifts, and my sleep schedule is irregular.
Could this have an impact?
(4) My menstrual flow stops on the fourth day, but I notice a little bit of brown discharge on the fifth or sixth day.
Is this normal?

Xiao Ling, 20~29 year old female. Ask Date: 2002/09/16

Dr. Wu Zongcheng reply Obstetrics and Gynecology


Hello, Miss Xiao Ling.
Infertility evaluations include 1.
Basal body temperature monitoring 2.
Hysterosalpingography 3.
Endocrine testing.
Irregular menstrual cycles and the presence of brown discharge afterward can indicate poor ovarian and uterine function, which can be improved with treatment.
Maintaining a more regular lifestyle can also help regulate the menstrual cycle.

Reply Date: 2002/09/16

More Info


Understanding infertility can be a complex and emotional journey for couples trying to conceive. Based on your concerns, let’s address your questions systematically.

1. What tests should you consider?
Given that you have been trying to conceive for over a year without success, it is advisable to undergo a comprehensive fertility evaluation. This typically includes:
- Hormonal Testing: Blood tests to check hormone levels, including thyroid hormones, prolactin, and reproductive hormones such as FSH, LH, and estradiol.

- Ovarian Reserve Testing: Tests such as an ultrasound to evaluate the number of follicles and blood tests for AMH (Anti-Müllerian Hormone) levels can provide insights into your ovarian reserve.

- Hysterosalpingography (HSG): This X-ray procedure checks for blockages in the fallopian tubes and assesses the shape of the uterine cavity.

- Semen Analysis: If applicable, your partner should also undergo a semen analysis to evaluate sperm count, motility, and morphology.

- Pelvic Ultrasound: This can help identify any structural issues such as fibroids or polyps.

2. Irregular menstrual cycles and their impact:
Your menstrual cycle variability (ranging from 28 to 35 days) can indeed affect your fertility. Irregular cycles may indicate issues with ovulation, which is crucial for conception. Conditions such as Polycystic Ovary Syndrome (PCOS) can lead to irregular cycles and may require specific management. Tracking ovulation through methods like basal body temperature charting or ovulation predictor kits can help identify your fertile window.

3. Impact of night shifts on fertility:
Working night shifts can disrupt your circadian rhythm and hormonal balance, potentially affecting ovulation and menstrual regularity. Studies suggest that shift work may be associated with fertility challenges due to altered hormone levels and stress. If possible, consider discussing your work schedule with your employer or exploring ways to minimize the impact of night shifts on your health.

4. Brown discharge after menstruation:
Experiencing a small amount of brown discharge a few days after your period can be normal. This discharge often consists of old blood that takes longer to exit the body. However, if this is accompanied by other symptoms such as pain, significant changes in your menstrual cycle, or if it persists, it would be wise to consult your healthcare provider for further evaluation.

In summary, it is essential to have a thorough evaluation by a fertility specialist who can guide you through the necessary tests and potential treatment options. Infertility can be influenced by various factors, including hormonal imbalances, lifestyle choices, and underlying medical conditions. Addressing these issues holistically can improve your chances of conception. Remember, you are not alone in this journey, and seeking support from healthcare professionals and support groups can be beneficial.

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