Bone marrow concerns?
I suffered a left humeral fracture, an open fracture of the left ulna, and a proximal left femur fracture due to a car accident.
However, it has been a year, and the left humerus has not healed.
Is there a need for bone grafting? If I undergo bone grafting, will the bone grow and heal? Will there be any long-term complications? If the bone is not healing, could it be due to avascular necrosis?
Yang Ling, 10~19 year old female. Ask Date: 2016/06/16
Dr. Shi Guozheng reply Orthopedics
A humeral fracture that does not heal may require bone grafting surgery.
The bone marrow you mentioned is likely referring to platelet-rich plasma (PRP), but its effectiveness is uncertain.
Reply Date: 2016/06/16
More Info
When dealing with non-healing fractures, particularly after significant injuries such as those sustained in a car accident, it is crucial to understand the various treatment options available, including the use of bone grafts and synthetic bone substitutes. In your case, where you have experienced a humeral fracture and an open ulnar fracture, the lack of healing after a year is concerning and warrants further investigation and intervention.
Understanding Non-Healing Fractures
Non-healing fractures, also known as non-unions, occur when a broken bone fails to heal properly within the expected time frame. Several factors can contribute to this condition, including inadequate blood supply, infection, mechanical instability, and the presence of bone necrosis (death of bone tissue). In your situation, it is essential to determine whether the bone has indeed died or if other factors are preventing healing.
Bone Graft Options
1. Autografts: This involves taking bone from another site in your body (often the iliac crest) and transplanting it to the non-healing fracture site. Autografts are considered the gold standard because they contain living cells and growth factors that promote healing.
2. Allografts: These are bone grafts taken from a donor (cadaver bone). While they can provide a scaffold for new bone growth, they do not contain living cells, which may limit their effectiveness compared to autografts.
3. Synthetic Bone Grafts: These include materials like calcium phosphate or bioactive glass. They can provide a scaffold for new bone to grow but may not be as effective as autografts in stimulating healing.
4. Bone Morphogenetic Proteins (BMPs): These are proteins that can be used in conjunction with grafts to promote bone healing. They are particularly useful in cases where traditional grafting may not be sufficient.
Use of Bone Cement
You mentioned the possibility of using "artificial bone paste" (likely referring to bone cement or synthetic graft materials). While these materials can help stabilize the fracture site and provide a scaffold for new bone growth, they do not guarantee that the bone will heal. The effectiveness of these materials can vary based on the individual case and the underlying reasons for the non-union.
Potential Complications and Considerations
- Healing: While bone grafts and synthetic materials can enhance the healing process, there is no absolute guarantee that they will lead to successful union, especially if other factors are at play (e.g., infection, inadequate blood supply).
- Post-operative Care: After any grafting procedure, careful monitoring and rehabilitation are crucial. You may need physical therapy to regain strength and mobility in the affected limb.
- Long-term Effects: There can be complications associated with grafting, including infection, graft rejection, or the development of arthritis in the joint near the fracture site.
Conclusion
In summary, if your humeral fracture has not healed after a year, it is essential to consult with an orthopedic specialist who can evaluate your specific situation. They may recommend imaging studies to assess the condition of the bone and determine the best course of action, which could include bone grafting or other interventions. Understanding the underlying reasons for the non-healing will be key to selecting the appropriate treatment and improving your chances of recovery.
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