Shingles in Pregnancy: Safety of Antiviral Medications for Mother and Baby - Dermatology

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Shingles


Hello doctor, I would like to ask if it is safe for a pregnant woman to take antiviral medication for shingles.
I am currently 26 weeks pregnant; will it affect the baby? If I have taken the medication for three days and there are no new rashes, can I stop taking the medication?

Eva, 30~39 year old female. Ask Date: 2016/06/29

Dr. Li Yufen reply Dermatology


Hello: The commonly used antiviral medication for shingles is classified as Category B in terms of pregnancy drug risk.
(Animal studies have shown no evidence of harm to the fetus, but there is a lack of well-designed controlled studies in pregnant women.
Alternatively, although animal studies indicate adverse effects on the embryo, controlled studies in pregnant women have not demonstrated a risk to the fetus.) Currently, the acute phase has passed, and there is no need for antiviral medication.
I am providing Dr.
Wang Xiuhuan's information on "Common Dermatological Medications: Pregnancy Drug Risk Classification - Safety Information for Medications in Pregnant Women" for your future reference: http://www.skin168.net/2012/03/skin-drugs-pregnancy-category.html Thank you!

Reply Date: 2016/06/29

More Info


When it comes to managing shingles (herpes zoster) during pregnancy, it is crucial to consider both the safety of antiviral medications for the mother and the potential effects on the developing fetus. Shingles is caused by the reactivation of the varicella-zoster virus, which can lead to painful rashes and other complications. Pregnant women who develop shingles should consult their healthcare provider for appropriate treatment options.

The primary antiviral medications used to treat shingles include acyclovir, valacyclovir, and famciclovir. According to the U.S. Food and Drug Administration (FDA), acyclovir is classified as a Category B drug for use during pregnancy. This means that animal studies have not shown any risk to the fetus, and there are no adequate and well-controlled studies in pregnant women. Valacyclovir, which is a prodrug of acyclovir, is also considered to be safe during pregnancy, although it is classified as Category B as well. Famciclovir has less data available, but it is generally considered to be safe based on its pharmacological profile.

In your case, being 26 weeks pregnant and having shingles, it is advisable to continue taking the antiviral medication as prescribed by your healthcare provider. Stopping the medication prematurely, especially after only three days, may not provide adequate treatment for the shingles outbreak. The antiviral medications work best when started early in the course of the illness, ideally within 72 hours of the rash appearing. If you have not developed new lesions and are feeling better, it is still important to follow your doctor's advice regarding the duration of treatment.

Additionally, while the risk of complications from shingles during pregnancy is relatively low, it is essential to monitor for any signs of complications, such as severe pain, secondary bacterial infections, or neurological symptoms. If you experience any unusual symptoms or have concerns about your health or the health of your baby, do not hesitate to contact your healthcare provider for further evaluation and guidance.

In summary, antiviral medications like acyclovir and valacyclovir are generally considered safe for use during pregnancy and can effectively manage shingles. It is important to adhere to your healthcare provider's recommendations regarding the duration of treatment and to communicate any concerns you may have. Your health and the health of your baby are paramount, and your healthcare provider is the best resource for personalized medical advice.

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