Mysterious Nerve Symptoms: Seeking Answers for Unexplained Numbness - Neurology

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I don't know what strange illness I have developed?


Hello Doctor, I don't know what strange illness I have, and I'm very scared.
I've seen several specialists without any results, and I'm feeling quite helpless and frustrated, not knowing what to do.
Please help me.
My limbs on one side experience unexplained numbness, which then spreads to my chest and head.
The duration varies from a few seconds to several minutes, with no specific time or posture.

It all started a year and a half ago (November 28, 2014) when I first experienced these symptoms.
I thought I was having a stroke (due to the numbness in my limbs).
The numbness occurred several times from noon to afternoon, and I was so frightened that I went to the emergency room.
The doctor there said I didn't appear to be having a stroke and suggested it might be due to anxiety, as my blood pressure was at 170.
The doctor prescribed antihypertensive medication and advised me to follow up with a general practitioner to investigate the cause.
(My usual blood pressure is between 120 and 130.)
In addition to the unexplained numbness in my limbs, I also experienced numbness in my chest and abdomen.
I underwent examinations in obstetrics and gastroenterology, but no abnormalities were found.
I then consulted a neurologist, who noted that I walked straight, my facial features were symmetrical, and my arm lift was balanced.
He mentioned that the sensations of numbness and tingling are very abstract and subjective, and he remarked that the line between neurology and psychiatry is very thin...
(I felt hurt, as I thought he was implying I was mentally ill.) Ultimately, he concluded that it was due to "mental fatigue caused by stress and emotions."
The first episode lasted about two months, and gradually, the symptoms disappeared.
I thought I had self-healed from this strange illness, but last week, I experienced another episode.
Interestingly, the first time it was on my left side, but this time it is on my right side.
This episode has lasted only two weeks, and I have seen several doctors without finding a cause.
I want to ignore it, but I'm also afraid that my body is warning me and that I might miss the opportunity for treatment.
Doctor, I am retired and have no work-related stress, I have a good relationship with my husband, and there are no financial issues.
I believe this illness is not due to stress.
I have some medical history to present; could you please help me understand what might be going on?
1.
I am a thyroid cancer patient, and I have been in follow-up for 11 years with normal results and indices.
2.
During my second radioactive iodine treatment, I developed type 2 herpes simplex, which occurs about once a month and has been ongoing for 11 years.
Could it be possible that the virus has affected other nerve ganglia?
3.
A year and a half ago, during a health check, my glycated hemoglobin was found to be 6.9, indicating diabetes.
Currently, I am not taking medication and am controlling it through exercise, with my glycated hemoglobin maintained between 5.8 and 6.
Could any of these medical histories be related to my strange illness? Thank you very much, and I look forward to your help!

Mrs. Chen, 50~59 year old female. Ask Date: 2016/07/02

Dr. Gao Chunde reply Neurology


The symptoms are reversible, indicating a functional transient disturbance, commonly seen in transient ischemic attacks or abnormal local neuronal discharges.
A neurologist will conduct a thorough examination and arrange appropriate further tests to determine the underlying cause.

Reply Date: 2016/07/02

More Info


Dear Patient,
I understand that you are feeling anxious and frustrated due to the unexplained symptoms you are experiencing. It’s important to acknowledge that your feelings are valid, especially when dealing with mysterious health issues. Based on the symptoms you described—numbness in one side of your body, which has now shifted from the left to the right side, along with sensations in your chest and head—there are several potential explanations to consider.

Firstly, the episodes of numbness and tingling you are experiencing could be related to a neurological condition. Conditions such as Multiple Sclerosis (MS) or Transverse Myelitis can cause similar symptoms, where the immune system attacks the protective covering of nerves, leading to sensory disturbances. However, these conditions typically present with additional neurological signs, which you mentioned were not present during your evaluations.

Another possibility is that your symptoms could be related to anxiety or panic attacks. The fact that your symptoms initially occurred during a stressful episode and that your blood pressure spiked suggests that anxiety could play a significant role. Anxiety can manifest physically, leading to sensations of numbness, tingling, or even a feeling of pressure in the chest. The mind and body are closely connected, and emotional stress can lead to physical symptoms that mimic neurological disorders.

Your medical history is also crucial in understanding your current symptoms. As a thyroid cancer survivor, it’s good to hear that your follow-ups have been normal. However, the presence of Type 2 diabetes can complicate matters. Diabetes can lead to peripheral neuropathy, which is characterized by numbness and tingling, particularly in the extremities. Although you are managing your blood sugar levels well, it’s essential to continue monitoring for any signs of neuropathy.

Regarding your question about the herpes simplex virus, while it is known to cause localized symptoms, it is less common for it to cause widespread neurological symptoms unless there is a significant outbreak affecting the nervous system. However, it’s worth discussing with your healthcare provider whether further evaluation for viral infections might be warranted.

Given the complexity of your symptoms and medical history, I recommend the following steps:
1. Neurological Evaluation: It may be beneficial to consult a neurologist who can perform a comprehensive evaluation, including imaging studies like MRI, to rule out any structural issues or lesions in the brain or spinal cord.

2. Psychological Assessment: Since your symptoms may have a psychological component, consider speaking with a mental health professional. They can help you explore any underlying anxiety or stress that may be contributing to your symptoms.

3. Diabetes Management: Continue to monitor your blood sugar levels closely. If you notice any changes in your symptoms, it may be worth discussing with your endocrinologist to ensure that your diabetes management is optimal.

4. Symptom Diary: Keeping a detailed diary of your symptoms, including when they occur, their duration, and any associated factors (like stress levels, diet, or physical activity), can provide valuable insights for your healthcare team.

5. Support Groups: Connecting with others who have similar experiences can be incredibly helpful. Support groups can provide emotional support and practical advice on managing symptoms.

In conclusion, while it can be distressing to experience unexplained symptoms, there are various avenues to explore for diagnosis and treatment. It’s essential to remain proactive in seeking answers and to communicate openly with your healthcare providers about your concerns. Remember, you are not alone in this journey, and there are resources available to help you navigate your health challenges.

Wishing you the best of health and peace of mind.

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