Does Extended Semen Liquefaction Time Affect Fertility? - Urology

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Semen liquefaction time


Hello! My husband recently had a semen analysis, and the results showed a liquefaction time of 60 minutes and a sperm count of 165 million/ml.
The report indicated that the liquefaction time is prolonged and the sperm count is high.
Will this affect fertility? The other results were normal.
Thank you!

Shou, 20~29 year old female. Ask Date: 2016/07/08

Dr. Chen Jiansheng reply Urology


Hello, Miss: Prolonged liquefaction time may affect sperm motility, and an excess of sperm can lead to thicker semen.
- Dr.
Chen Chien-Sheng, Urology Department, New Taipei City Hospital.

Reply Date: 2016/07/08

More Info


Extended semen liquefaction time can indeed have implications for fertility, although the effects can vary depending on individual circumstances. Semen liquefaction is a critical process that occurs after ejaculation, where the initially gel-like semen transforms into a liquid state, allowing sperm to swim freely and reach the egg for fertilization. The normal liquefaction time is typically between 15 to 30 minutes. When liquefaction takes longer than this, as in your husband's case where it took 60 minutes, it may indicate underlying issues that could potentially affect fertility.

In your husband's semen analysis, the sperm count of 165 million/ml is considered excellent, as normal sperm counts are generally above 15 million/ml. However, the prolonged liquefaction time could suggest a few things. One possibility is that there may be an abnormality in the seminal plasma, which could affect the sperm's ability to swim effectively. If the semen does not liquefy properly, it may hinder the sperm's motility, making it more challenging for them to navigate through the female reproductive tract to reach the egg.

Moreover, while a high sperm count is a positive factor, the overall quality of the sperm, including motility (the ability to move) and morphology (the shape and structure), is also crucial for successful fertilization. If the sperm are unable to swim effectively due to the prolonged liquefaction time, it could lead to difficulties in conception, even with a high sperm count.

It’s also important to consider that prolonged liquefaction time can sometimes be associated with infections or inflammation in the reproductive tract, which could further impact fertility. Therefore, it may be advisable for your husband to consult with a urologist or a fertility specialist to explore the potential causes of the extended liquefaction time and to assess whether any treatment is necessary.

In terms of fertility, the combination of factors such as sperm count, motility, morphology, and liquefaction time all play a role. If the other parameters of the semen analysis are normal, and if the sperm are motile and morphologically normal, there may still be a chance for conception, but the prolonged liquefaction time could complicate the process.

In conclusion, while your husband's sperm count is excellent, the extended liquefaction time could potentially affect fertility. It would be beneficial to follow up with a healthcare professional who specializes in male fertility to further evaluate the situation and determine if any interventions are needed. They may recommend additional tests or treatments to improve the liquefaction time and overall sperm quality, thereby enhancing the chances of conception.

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