Pregnant While on Birth Control and Ovulation Pills: Risks and Concerns - Obstetrics and Gynecology

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Taking birth control pills and ovulation medication, only to discover that you are pregnant?


Hello, doctor.
My last menstrual period started on June 24.
I had intercourse on July 10 and took emergency contraception (Postcoital contraceptive - Yuzpe regimen) on July 12.
I experienced some abdominal discomfort, so I went to the hospital for an examination on July 14, where I had a urine test and an abdominal ultrasound.
The results showed that I was not pregnant and there were no abnormalities, but I was informed that I was not ovulating.
I was prescribed ovulation medication.
My menstrual period started on July 19, but the flow was very light (I have experienced light flow before).
On July 21, I started taking the ovulation medication for five consecutive days (clinic), but I noticed that the symptoms during my period felt a bit different.
I bought a pregnancy test and it showed two lines.
Will this affect the health of the fetus? I am currently very worried because I previously heard from a doctor that contraceptive pills and hormonal medications (ovulation drugs) can lead to fetal malformations such as hypospadias, Down syndrome, cleft lip, anencephaly, congenital heart disease, etc.
I would like to ask the doctor, is clomiphene classified as a Category X medication?

Niming, 30~39 year old female. Ask Date: 2016/07/26

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, the medication that may affect you is the emergency contraceptive pill - Yu-Ting tablet.
Generally, it is not recommended to continue the pregnancy, and it is advisable to consult your regular obstetrician for their opinion.
Wishing you good health.

Reply Date: 2016/07/26

More Info


When a pregnant woman finds herself in a situation where she has been taking birth control pills and ovulation medications, it raises several concerns regarding the health of the fetus and the implications for the pregnancy. The situation you described involves the use of emergency contraception (Plan B) and ovulation-inducing medications, which can lead to anxiety about potential risks to the developing baby.

First and foremost, it is essential to understand that the use of emergency contraception, such as Plan B (levonorgestrel), is generally considered safe and does not have long-term effects on future pregnancies. If taken as directed, it is designed to prevent ovulation and fertilization, and it is not effective if a woman is already pregnant. Therefore, if a pregnancy test shows positive results after taking emergency contraception, it indicates that the contraception was not effective in preventing ovulation or fertilization during that cycle.

Regarding the use of ovulation medications like clomiphene citrate (often referred to as Clomid), it is classified as a Category X medication by the FDA when used in pregnancy. This classification indicates that studies in animals or humans have demonstrated fetal abnormalities, and the risks involved in using the drug in pregnant women clearly outweigh any potential benefits. However, clomiphene is typically prescribed to women who are trying to conceive, and its use is not recommended once pregnancy is confirmed.

The concerns you mentioned regarding potential congenital anomalies, such as hypospadias, Down syndrome, cleft lip, anencephaly, and congenital heart defects, are valid. However, it is important to note that while some studies have suggested a potential association between the use of certain medications and specific birth defects, the overall risk remains relatively low. The majority of pregnancies, even those involving the use of fertility medications, result in healthy outcomes.

If you are pregnant and have concerns about the medications you have taken, it is crucial to consult with your healthcare provider. They can provide personalized advice based on your medical history and the specifics of your situation. Additionally, they may recommend a detailed ultrasound or further testing to monitor the health of the fetus and ensure that any potential issues are addressed early.

In summary, while there are risks associated with the use of certain medications during pregnancy, the overall outcome for many women who have taken these medications is positive. It is essential to maintain open communication with your healthcare provider, who can guide you through this process and help alleviate your concerns. Regular prenatal care is vital for monitoring the health of both the mother and the fetus, ensuring that any potential risks are managed appropriately.

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