Anemia: Is It Mediterranean Anemia? - Cardiology

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I would like to inquire if it is Mediterranean anemia?


Hello Doctor, thank you for your previous response.
I found my earlier prenatal check-up report and would like to ask if you can identify the type of anemia from the serum tests: V.D.R.L (-), HIV Ag/Ab Combo 0.11 (-), Rubella IgG (+).
The blood test results are as follows: WBC 7440, RBC 4.41, Hb 9.5, Hct 32.1, MCV 72.8, MCH 21.5, MCHC 29.6, Platelet 306, Blood Type [O], RH Factor RH (+).
Thank you for patiently reviewing my questions.

JJ, 20~29 year old female. Ask Date: 2016/08/02

Dr. He Dongjin reply Cardiology


Hello, I am not sure how long ago this report was.
This does not appear to be a report of microcytic anemia, nor does it resemble thalassemia.
As for the specific type, I am unable to determine that.
I recommend that if you are still experiencing discomfort, you should consult a hematologist for further evaluation.
Best wishes from Changhua Hospital.

Reply Date: 2016/08/02

More Info


Anemia is a condition characterized by a deficiency in the number or quality of red blood cells (RBCs), which can lead to reduced oxygen transport in the body. There are various types of anemia, and understanding the specific type is crucial for effective treatment. Based on the blood test results you provided, we can analyze the data to determine the potential type of anemia.

Your blood test results indicate the following:
- WBC (White Blood Cells): 7440 (normal range)
- RBC (Red Blood Cells): 4.41 (normal range)
- Hb (Hemoglobin): 9.5 g/dL (low)
- Hct (Hematocrit): 32.1% (low)
- M.C.V (Mean Corpuscular Volume): 72.8 fL (low)
- M.C.H (Mean Corpuscular Hemoglobin): 21.5 pg (low)
- M.C.H.C (Mean Corpuscular Hemoglobin Concentration): 29.6 g/dL (normal)
- Platelet Count: 306 (normal range)
- Blood Type: O, Rh Factor: Rh (+)
The key indicators here are the low hemoglobin (Hb) and hematocrit (Hct) levels, along with low mean corpuscular volume (M.C.V). The low M.C.V suggests that the red blood cells are smaller than normal, which is a characteristic feature of microcytic anemia. The most common cause of microcytic anemia is iron deficiency, but it can also be associated with thalassemia or anemia of chronic disease.

Given your question about Mediterranean anemia, it is important to clarify that Mediterranean anemia typically refers to thalassemia, a genetic blood disorder that affects hemoglobin production. Thalassemia is more prevalent in individuals of Mediterranean descent, but it can occur in other populations as well. The presence of low M.C.V and low M.C.H in your results could indicate a possibility of thalassemia, especially if there is a family history of the condition or if you belong to a demographic group where thalassemia is more common.

To further investigate the type of anemia, additional tests may be necessary, including:
1. Iron Studies: This includes serum iron, ferritin, and total iron-binding capacity (TIBC) to assess iron levels in the body.

2. Hemoglobin Electrophoresis: This test can help identify different types of hemoglobin and can confirm or rule out thalassemia.

3. Reticulocyte Count: This measures the number of young red blood cells and can help determine if the bone marrow is responding appropriately to the anemia.

In conclusion, based on the provided blood test results, you may be experiencing microcytic anemia, which could be due to iron deficiency or potentially thalassemia. It is essential to consult with a healthcare provider who can interpret these results in the context of your overall health, medical history, and any symptoms you may be experiencing. They can guide you through the necessary diagnostic steps and treatment options tailored to your specific condition. If you have further questions or concerns, please do not hesitate to reach out for more information.

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