RU486: Unusual Bleeding After Taking Emergency Contraceptive - Obstetrics and Gynecology

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RU486, also known as mifepristone, is a medication


I took RU486 on July 10th, and the doctor said everything was cleared out.
However, on the 26th, I suddenly started bleeding quite heavily.
The day before that, I took emergency contraception.
The doctor mentioned that I would get my period on August 10th, but it still hasn't arrived.
What could be the reason for this?

Cheng, 20~29 year old female. Ask Date: 2016/08/20

Dr. Huang Yiwen reply Obstetrics and Gynecology


Hello Ms.
Cheng: The bleeding you experienced on the 26th may be related to your use of RU486.
Generally, after a medical or surgical abortion, the first menstrual period may be delayed by about one to two weeks.
I recommend that you wait another two weeks to see what happens.
If you are still concerned, you can certainly take a urine test to find out the answer.

Reply Date: 2016/08/20

More Info


RU486, also known as mifepristone, is a medication commonly used for medical abortion and is sometimes utilized in conjunction with misoprostol for this purpose. It works by blocking the hormone progesterone, which is necessary for the continuation of pregnancy. After taking RU486, it is not uncommon for individuals to experience unusual bleeding, which can be a source of concern.

In your case, you mentioned taking RU486 on July 10 and subsequently experiencing significant bleeding around July 26, after having taken emergency contraception the day before. It is important to understand that the bleeding you experienced could be related to the effects of RU486, as it can cause a range of bleeding patterns. Following the use of RU486, some individuals may experience heavy bleeding, which can include the passage of blood clots and tissue, as the body expels the contents of the uterus.

The timeline you provided indicates that your doctor anticipated your next menstrual period would arrive around August 10. However, it is not unusual for the first menstrual cycle following a medical abortion to be delayed. Factors such as hormonal fluctuations, the body’s adjustment after the abortion, and the use of emergency contraception can all influence the timing of your next period. After a medical abortion, it is common for the menstrual cycle to take some time to regulate, and it may be delayed by a week or more.

If you have not had your period by now, it could be due to several reasons:
1. Hormonal Changes: After taking RU486, your body undergoes significant hormonal changes, which can delay the return of your menstrual cycle.

2. Emergency Contraceptive Effects: The emergency contraceptive pill can also affect your menstrual cycle, potentially causing delays or irregularities.

3. Pregnancy: Although you have taken RU486, there is still a possibility of residual pregnancy tissue remaining, which could lead to continued hormonal activity and delay menstruation. However, if you have had a follow-up appointment and your doctor confirmed that the abortion was complete, this is less likely.

4. Stress and Other Factors: Emotional and physical stress can also impact your menstrual cycle, leading to delays.

Given your situation, if you are concerned about the absence of your period or if you experience any other unusual symptoms (such as severe pain, fever, or excessive bleeding), it is advisable to consult your healthcare provider. They may recommend a pregnancy test to rule out any residual pregnancy or other potential issues. Additionally, they can perform an ultrasound if necessary to ensure that the uterus is clear of any remaining tissue.

In summary, while it is common for the first period after taking RU486 to be delayed, it is essential to monitor your symptoms and maintain communication with your healthcare provider. They can provide personalized advice and reassurance based on your specific circumstances.

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