Unilateral Sensory Changes: Possible Neurological Concerns - Neurology

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There is a slight difference in sensation on the left side of the face and the limbs?


Hello Doctor, recently I've noticed that the left side of my face and my limbs feel different compared to the right side.
There is no soreness or numbness, and I usually don't feel any difference.
However, when I touch them, they feel slightly different.
I can still sense cold, heat, and pain, and this has been persistent rather than sudden.
I looked it up online, and I found that unilateral issues could indicate a stroke, but I don't have high blood pressure or diabetes, and I don't experience soreness or numbness.
What could be the problem?

yang, 20~29 year old female. Ask Date: 2016/08/23

Dr. Gao Chunde reply Neurology


Considering that there may be an issue with the sensory function of the brain's internal pathways, there are various potential causes.
Stroke is one of the vascular causes, but other possibilities include inflammatory and compressive factors.
It is recommended to visit a hospital's neurology department for further evaluation.

Reply Date: 2016/08/23

More Info


Hello! Thank you for your question regarding unilateral sensory changes. It’s understandable to be concerned when you notice differences in sensation between the left and right sides of your body, especially when it comes to your face and limbs. While you mentioned that you do not experience pain or numbness, the fact that you perceive a difference in how your left side feels compared to your right side is noteworthy.

Unilateral sensory changes can indeed be associated with various neurological concerns. While conditions like stroke are often highlighted in discussions about unilateral symptoms, they are not the only possibilities. Given that you do not have risk factors such as high blood pressure or diabetes, it is important to consider other potential causes.

1. Neurological Assessment: The first step in understanding your symptoms is to undergo a thorough neurological evaluation. A neurologist can perform a physical examination and may order imaging studies, such as an MRI or CT scan, to assess the brain and spinal cord for any abnormalities. These tests can help rule out conditions like stroke, tumors, or other structural issues.

2. Peripheral Nervous System Issues: Sometimes, unilateral sensory changes can arise from issues in the peripheral nervous system, such as nerve compression or injury. Conditions like carpal tunnel syndrome or ulnar nerve entrapment can lead to altered sensations in specific areas, although these usually present with pain or tingling.

3. Multiple Sclerosis (MS): Another condition to consider is multiple sclerosis, which can cause sensory changes and may present with unilateral symptoms. MS is an autoimmune disorder that affects the central nervous system and can lead to a variety of neurological symptoms.

4. Transient Ischemic Attack (TIA): Even in the absence of traditional risk factors, a transient ischemic attack, or "mini-stroke," can occur and may present with temporary sensory changes. It’s crucial to seek medical attention if you experience any sudden changes in sensation, even if they resolve quickly.

5. Psychogenic Factors: In some cases, sensory changes can be linked to psychological factors. Stress, anxiety, or somatic symptom disorders can manifest as physical sensations without an identifiable medical cause. A mental health evaluation may be beneficial if other medical assessments do not reveal a clear cause.

6. Other Conditions: There are various other conditions, such as migraines with aura, that can cause temporary sensory disturbances. Additionally, vitamin deficiencies (like B12 deficiency) or metabolic disorders can also lead to sensory changes.

In conclusion, while your symptoms may not immediately suggest a severe condition like a stroke, it is essential to consult with a healthcare professional for a comprehensive evaluation. They can help determine the underlying cause of your unilateral sensory changes and recommend appropriate treatment or management strategies. Early intervention is key in addressing any potential neurological issues, so don’t hesitate to seek medical advice.

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