Do Antibiotics Affect Birth Control Pills? the Myths and Facts - Obstetrics and Gynecology

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Antibiotic contraceptives


Recently, I visited a gynecologist for a vaginal infection, and the doctor prescribed the following medications: Ampicillin 500mg (ampicillin capsules), Anliton 500mg, and Suprogel.
I read online that Ampicillin may affect oral contraceptives, but the gynecologist said there would be no conflict.
Can you clarify whether this type of antibiotic affects birth control pills? Additionally, for a Candida infection, does the male partner (who is uncircumcised) need to be treated as well? Some say yes, while others say no.

Miles, 20~29 year old female. Ask Date: 2016/08/27

Dr. Zhang Kunmin reply Obstetrics and Gynecology


Hello, the inquirer: Certain antibiotics (Penicillin, Cephalosporins, Erythromycin, Sulfonamides, Bactrim, Chloramphenicol) may reduce the beneficial gut flora that aids in absorption, potentially decreasing the effectiveness of contraceptive pills.
If the male partner exhibits symptoms of a yeast infection, applying an antifungal cream is sufficient.
Thank you! Wishing you peace and health, Dr.
Zhang.

Reply Date: 2016/08/27

More Info


The question of whether antibiotics affect birth control pills is a common concern among women who are using hormonal contraceptives. The short answer is that most antibiotics do not interfere with the effectiveness of birth control pills. However, there are some exceptions and nuances that are important to understand.

Understanding Antibiotics and Birth Control Pills
1. General Interaction: Most antibiotics, including commonly prescribed ones like ampicillin, do not significantly impact the effectiveness of hormonal contraceptives. The concern arises from the belief that antibiotics may alter the gut flora or affect the metabolism of hormones in the liver, potentially leading to decreased effectiveness of the contraceptive. However, extensive research has shown that this is not the case for the majority of antibiotics.

2. Specific Antibiotics: The only antibiotic that has been consistently shown to potentially reduce the effectiveness of birth control pills is rifampin, which is used to treat tuberculosis and some other infections. Rifampin induces liver enzymes that can increase the metabolism of estrogen and progestin, the hormones found in many contraceptive pills, thereby reducing their effectiveness.

3. Ampicillin and Other Antibiotics: In your case, ampicillin is not known to interfere with the effectiveness of birth control pills. Your gynecologist's advice aligns with current medical understanding. Other antibiotics, such as tetracycline and penicillin, have also been studied and found not to affect hormonal contraceptives.

4. Myths and Misunderstandings: The myth that all antibiotics affect birth control pills likely stems from early studies and anecdotal reports. Many women have been advised to use backup contraception when taking antibiotics, but this is generally unnecessary unless the antibiotic is rifampin or a similar medication.

Candida Infections and Treatment
Regarding your question about a Candida (yeast) infection, it is important to note that while yeast infections are common, the treatment typically focuses on the individual experiencing symptoms. If the male partner is asymptomatic and does not have any signs of infection, treatment is usually not necessary. However, if there are recurrent infections or if the male partner has symptoms (such as irritation or discharge), it may be advisable for him to seek treatment as well.

In summary, based on current medical evidence, antibiotics like ampicillin do not affect the efficacy of birth control pills. It is always best to consult with your healthcare provider regarding any medications you are taking and their potential interactions. If you have further concerns about your contraceptive method or the treatment for your yeast infection, don't hesitate to discuss these with your doctor for personalized advice.

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