High Blood Pressure vs. Autonomic Nervous System Disorders - Cardiology

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Hypertension or autonomic nervous system dysfunction?


Hello Doctor, two months ago I experienced long-term stress, insomnia, and often hear my own heartbeat.
I have shoulder and neck pain.
My blood pressure sometimes spikes suddenly to 170/100 (this has happened five times in the past two months, but it always comes down).
I have lost 7 kilograms in a month.
I went to the emergency room three times, and the ECGs were normal, as well as the X-rays.
My blood pressure averages between 115-140/70-90.
Whenever my blood pressure spikes to 150/90, I immediately take the propranolol and Xanax prescribed by my doctor, and my blood pressure drops right away.
In early August, I had a health check-up, and the echocardiogram and ECG were normal, but there was mild intimal thickening in the carotid arteries, and my cholesterol and triglycerides were slightly elevated.
My current weight is 73.5 kilograms.
My parasympathetic nervous system is relatively high.
Before taking propranolol, my heart rate at home was sometimes between 83-109, but after taking it, it is between 60-80.
Do I need to undergo additional coronary CT angiography? Thank you.
I am currently taking propranolol and fludiazepam, and half a tablet of Seroquel before bed.
I would like to know if these medications have any side effects on the liver and kidneys.
Thank you.

Terence, 40~49 year old female. Ask Date: 2016/09/02

Dr. He Dongjin reply Cardiology


Hello, autonomic nervous system dysfunction is not caused by high blood pressure.
Propranolol and fludiazepam have no side effects on the liver and kidneys, so please rest assured.
Currently, there is no need for additional coronary computed tomography angiography.
Changhua Hospital cares about you.

Reply Date: 2016/09/02

More Info


Understanding the relationship between high blood pressure and autonomic nervous system disorders is crucial, especially in the context of your symptoms and medical history. Based on the information you provided, it appears that your high blood pressure episodes may be linked to stress and anxiety, which can significantly impact the autonomic nervous system (ANS).


Autonomic Nervous System and Blood Pressure
The autonomic nervous system is divided into two main branches: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system is responsible for the "fight or flight" response, which can lead to increased heart rate and elevated blood pressure during stressful situations. Conversely, the parasympathetic nervous system promotes a "rest and digest" state, helping to lower heart rate and blood pressure.

In your case, the episodes of high blood pressure (170/100) occurring during periods of stress and anxiety suggest that your sympathetic nervous system may be overactive. This is a common response to stress, and it can lead to temporary spikes in blood pressure. The fact that your blood pressure normalizes after taking propranolol (a beta-blocker) indicates that this medication effectively reduces the sympathetic nervous system's influence on your heart rate and blood pressure.


Diagnostic Considerations
Given your symptoms and the results of your previous tests (normal ECG, chest X-ray, and echocardiogram), it seems that your heart is functioning well. However, the mild thickening of the carotid artery's intima could indicate early vascular changes, which are often associated with chronic stress and elevated cholesterol levels. While your blood pressure readings are generally within a manageable range, the occasional spikes warrant further investigation.

You asked about the necessity of a coronary artery CT scan. This imaging test can help assess the presence of coronary artery disease, especially if you have risk factors such as high cholesterol and a family history of heart disease. However, it may not be immediately necessary if your heart function tests are normal and you are managing your blood pressure effectively with medication. Discussing this with your cardiologist would provide clarity on whether this test is appropriate for you at this time.


Medication and Side Effects
Regarding the medications you are currently taking—propranolol, fludiazepam, and the sleep aid—you should be aware of potential side effects. Propranolol can cause fatigue, dizziness, and in some cases, may affect liver function, although this is rare. Fludiazepam, a benzodiazepine, can lead to dependence if used long-term and may cause drowsiness, confusion, or impaired coordination. The sleep aid, while effective for insomnia, can also have side effects, particularly if used regularly.

Both propranolol and fludiazepam can impact liver metabolism, so it’s essential to monitor liver function through regular blood tests, especially if you have any pre-existing liver conditions. Additionally, if you experience any unusual symptoms, such as jaundice (yellowing of the skin or eyes), dark urine, or severe fatigue, you should contact your healthcare provider immediately.


Lifestyle Modifications
In addition to medication, consider lifestyle changes to help manage stress and blood pressure. Regular physical activity, a balanced diet low in saturated fats and high in fruits and vegetables, adequate hydration, and mindfulness practices such as yoga or meditation can significantly improve your overall well-being and help regulate blood pressure.


Conclusion
In summary, your symptoms and medical history suggest a connection between stress, autonomic nervous system dysregulation, and episodes of high blood pressure. While your current medications are helping manage your symptoms, it’s essential to maintain regular follow-ups with your healthcare provider to monitor your condition and adjust treatment as necessary. If you have further concerns about your medications or the need for additional tests, do not hesitate to discuss them with your doctor. Your health is a priority, and proactive management is key to maintaining it.

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