Does Nail Lacquer Really Treat Fungal Nail Infections? - Dermatology

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Topical medication for onychomycosis - nail lacquer?


Hello, doctor! There is a product on the market advertised for treating toenail fungus called "nail lacquer." Does it really have any efficacy? I am currently considering using a topical treatment since my symptoms are still mild.
Thank you for your response!

Xiao Bing, 20~29 year old female. Ask Date: 2016/09/08

Dr. Li Yufen reply Dermatology


Hello: For a detailed introduction to onychomycosis (fungal nail infection), you can refer to the article on the Dermatology Expert Health website at http://www.drskincare.com.tw/Qa/Index.aspx?CID=12.
It is recommended that you first consult a dermatologist to confirm whether it is onychomycosis, and then decide on the subsequent treatment options at http://www.derma.org.tw/user_finddoctor.php.
Thank you!

Reply Date: 2016/09/08

More Info


Nail lacquer, specifically antifungal nail lacquer, has gained popularity as a treatment option for fungal nail infections, commonly known as onychomycosis. The effectiveness of these products can vary based on several factors, including the specific formulation, the severity of the infection, and the individual's response to treatment.

Antifungal nail lacquers, such as ciclopirox (Penlac) and amorolfine, are designed to be applied directly to the affected nails. They work by penetrating the nail plate and targeting the fungal cells, thereby inhibiting their growth. Clinical studies have shown that these treatments can be effective, particularly for mild to moderate cases of onychomycosis. However, they are generally less effective than systemic antifungal medications, such as terbinafine (Lamisil) or itraconazole (Sporanox), especially in more severe infections.

One of the main advantages of using nail lacquer is its localized application, which minimizes systemic side effects that can occur with oral antifungal medications. This makes nail lacquers a suitable option for patients who may be at risk for adverse effects from systemic treatments, such as those with liver disease or those taking multiple medications that could interact with oral antifungals.

However, it is important to note that nail lacquer treatments require consistent and proper application over an extended period, often several months, to achieve satisfactory results. Patients must apply the lacquer as directed, typically once or twice a week, and maintain good nail hygiene to enhance the treatment's effectiveness. Additionally, the success rate of nail lacquers can be influenced by factors such as the type of fungus causing the infection, the extent of nail involvement, and the patient's overall health.

For individuals with only mild symptoms, antifungal nail lacquer can be a reasonable first-line treatment. However, if the infection is more extensive or if there is no improvement after a few months of using the lacquer, it may be advisable to consult a healthcare professional for further evaluation and potential systemic treatment options.

In summary, antifungal nail lacquers can be effective for treating mild fungal nail infections, but their efficacy may be limited compared to systemic treatments. If you are considering this treatment option, it is essential to follow the application instructions carefully and monitor your progress. If symptoms persist or worsen, seeking medical advice is crucial to ensure appropriate management of the infection.

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