Tonsillitis and Lymph Node Swelling: Causes and Treatments - Otolaryngology

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Tonsillar suppuration and enlargement of the lymph nodes behind the ear and at the occipital region?


Hello Doctor: About two weeks ago, I experienced a sore throat and noticed purulent tonsillitis, along with swollen and painful lymph nodes in my jaw.
After seeing a doctor, I took Augmentin 1g and steroids for three days, and my symptoms disappeared.
However, three days after stopping the medication, the pain returned.
Upon returning to the clinic, I was prescribed the same medication, and after taking it, my symptoms improved.
However, when I licked the back of my tongue, I noticed that my tonsils seemed to have many small grooves, and one side of the tonsil had developed something resembling small granulation tissue.
The doctor mentioned that this could be a change in the mucosa due to inflammation.
After taking antibiotics for about six days, I noticed that the lymph nodes behind both ears were swollen and painful.
After continuing the medication, they became softer (the largest about 0.5 cm), some disappeared, but some remained.

I have a few questions for you, Doctor:
1.
Why did the lymph nodes swell while I was halfway through the medication for tonsillitis?
2.
After taking antibiotics for nine days, I measured my temperature and had a slight fever (oral temperature 37.3°C), and it seems that the lymph nodes in my jaw are a bit swollen again.
The doctor prescribed another three days of Augmentin, reducing the dosage to 626 mg three times a day, stating that there is improvement.
Why are the lymph nodes still swollen, and why do I have a slight fever?
3.
Do I need to undergo further examinations (such as blood tests or biopsies)? Thank you, Doctor.

Hsiu, 20~29 year old female. Ask Date: 2016/09/12

Dr. Zheng Jueyi reply Otolaryngology


Hello: 1.
Enlargement may be caused by an infection.
2.
It is unrelated to antibiotic resistance.
3.
It is recommended to continue follow-up visits for treatment.
If there are concerns about other changes, you may discuss with your clinic physician and consider referral for further treatment.
Wishing you safety and health.
Sincerely, Dr.
Cheng Jue-Yi, Director of the Department of Otolaryngology, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2016/09/12

More Info


Tonsillitis, an inflammation of the tonsils, often leads to symptoms such as sore throat, difficulty swallowing, and swollen lymph nodes, particularly in the neck. The condition can be caused by viral or bacterial infections, with streptococcal bacteria being a common culprit. When tonsillitis is present, the body's immune response is activated, leading to the swelling of lymph nodes as they work to filter out the infection.

In your case, the initial treatment with Augmentin (a combination of amoxicillin and clavulanate) and steroids likely helped reduce inflammation and manage symptoms. However, the recurrence of pain and swelling after stopping the medication suggests that the underlying infection may not have been fully resolved or that there could be a secondary infection or complication.

1. Why did the lymph nodes swell again while on medication?
The swelling of lymph nodes during treatment can occur for several reasons. First, the immune system is actively responding to the infection, and lymph nodes can swell as they produce more immune cells to fight off the pathogens. Additionally, if the antibiotic is not fully effective against the specific bacteria causing the infection, the lymph nodes may continue to swell despite treatment. It’s also possible that the inflammation from the tonsillitis itself can cause nearby lymph nodes to react, leading to swelling.

2. Why are the lymph nodes still swollen and there is a slight fever after nine days of antibiotics?
Persistent swelling of lymph nodes and mild fever can indicate that the infection is still present or that there is a new infection developing. The reduction in dosage of Augmentin may also affect the efficacy of the treatment. In some cases, bacteria can develop resistance to antibiotics, making them less effective. Additionally, the presence of other conditions, such as viral infections or even non-infectious causes like autoimmune responses, can contribute to ongoing symptoms. It’s essential to monitor these symptoms closely, as they can provide clues about the underlying issue.

3. Should you undergo further testing?
Given the persistence of symptoms, it may be prudent to consider further evaluation. Blood tests can help assess the overall immune response and check for signs of infection or inflammation. If there is concern about the nature of the lymph node swelling, imaging studies such as an ultrasound may be warranted to evaluate the lymph nodes more closely. In some cases, a biopsy may be necessary if there is suspicion of a more serious condition, such as lymphoma or another malignancy, especially if the lymph nodes do not respond to treatment or continue to grow.

In summary, tonsillitis can lead to significant lymph node swelling as part of the body's immune response. While antibiotics can help, they may not always resolve the infection completely, leading to recurrent symptoms. Close monitoring and further evaluation may be necessary to ensure proper treatment and to rule out any serious underlying conditions. If symptoms persist or worsen, it is crucial to follow up with your healthcare provider for a comprehensive assessment and tailored treatment plan.

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