Test Timeliness and Normal Values for Testicular Cancer Markers - Urology

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Timeliness of Testing for Testicular Cancer Markers


Hello, doctor! A few days ago, I underwent testing for testicular cancer due to concerns, and the results showed AFP=1.40, BETA-HCG=<0.500, and LDH=128.
Should I consider these values to be normal? Additionally, how long are these markers effective for monitoring?

Niming, 20~29 year old female. Ask Date: 2016/09/18

Dr. Sun Hongshun reply Urology


Hello, those indicators are just current values.
Even if cancer markers are normal, it cannot guarantee that the patient is 100% free of cancer.
It is advisable to consult a clinic for examination if you are feeling unwell.

Reply Date: 2016/09/18

More Info


When it comes to testicular cancer markers, the values you've provided—AFP (Alpha-fetoprotein) at 1.40, Beta-HCG (Beta-human chorionic gonadotropin) at <0.500, and LDH (Lactate dehydrogenase) at 128—are indeed within the normal range for most laboratories.
To elaborate, AFP is a protein that is typically elevated in certain types of testicular cancer, particularly non-seminomatous germ cell tumors. Normal levels of AFP are generally considered to be less than 10 ng/mL, so your value of 1.40 ng/mL is well within the normal limits. Beta-HCG is another marker that can be elevated in testicular cancer, especially in choriocarcinoma, but your result of <0.500 ng/mL indicates that it is not elevated. LDH is a marker that can indicate tissue damage and is not specific to cancer; however, elevated levels can be associated with various malignancies, including testicular cancer. A normal LDH level varies by laboratory but is typically around 140-280 U/L, so your level of 128 U/L is also normal.

It's important to note that while these markers can provide valuable information, they are not definitive for diagnosing or ruling out cancer. Normal levels do not guarantee that a person does not have cancer, and conversely, elevated levels do not confirm cancer. Therefore, if you have any symptoms or concerns, it is crucial to consult with a healthcare provider for further evaluation.

Regarding the timeliness of these tests, tumor marker tests like AFP, Beta-HCG, and LDH can be performed relatively quickly, often within a few days. However, the interpretation of these results should be done in conjunction with clinical findings and imaging studies, if necessary. Regular monitoring may be recommended, especially if there are any risk factors or symptoms present.

In summary, your test results appear to be normal, but it is essential to maintain open communication with your healthcare provider about any ongoing concerns or symptoms. Regular follow-ups and possibly imaging studies may be warranted based on your medical history and risk factors. Always remember that early detection and intervention are key in managing any potential health issues.

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