Can Oral Accutane Be Prescribed by Dermatologists in Clinics? - Dermatology

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Hello, I would like to inquire about oral isotretinoin?


Can oral isotretinoin be prescribed by general clinics or dermatology offices, or is it only available at large hospitals since it is prohibited for sale in pharmacies? Thank you.

Chen, 20~29 year old female. Ask Date: 2016/09/21

Dr. Li Yufen reply Dermatology


Hello: Not all dermatology clinics stock oral retinoids.
I suggest you call ahead to inquire.
Thank you!

Reply Date: 2016/09/21

More Info


Yes, oral Accutane (isotretinoin) can be prescribed by dermatologists in clinics, not just in large hospitals. Dermatologists are specially trained to manage severe acne and other skin conditions, and they have the authority to prescribe isotretinoin as part of a comprehensive treatment plan. However, there are specific guidelines and protocols that must be followed when prescribing this medication due to its potential side effects and risks.

Isotretinoin is a powerful medication used primarily for severe acne that has not responded to other treatments. It works by reducing the size and activity of sebaceous (oil) glands in the skin, leading to decreased oil production and, consequently, fewer acne lesions. While it can be highly effective, isotretinoin is also associated with a range of side effects, some of which can be serious. These include dry skin, chapped lips, nosebleeds, and more severe risks such as liver damage, increased cholesterol levels, and teratogenic effects (causing birth defects if taken during pregnancy).

Due to these risks, dermatologists must ensure that patients are fully informed about the potential side effects and the importance of adhering to safety measures, especially regarding pregnancy prevention. In the United States, the iPLEDGE program is a risk management program designed to prevent fetal exposure to isotretinoin. Patients, prescribers, and pharmacies must all comply with this program to ensure safe use of the medication.

When a dermatologist prescribes isotretinoin, they typically conduct a thorough evaluation of the patient's medical history, current medications, and any contraindications. They may also require baseline lab tests to assess liver function and lipid levels before starting treatment and periodically during treatment to monitor for any adverse effects.

In conclusion, while isotretinoin can be prescribed in outpatient dermatology clinics, it is crucial for patients to be aware of the responsibilities that come with this treatment. Regular follow-up appointments, lab tests, and adherence to safety protocols are essential to ensure the safe and effective use of this medication. If you are considering isotretinoin for your acne, it is advisable to consult with a qualified dermatologist who can guide you through the process and monitor your treatment closely.

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