the Use of LedaMed for Treating Genital Warts - Obstetrics and Gynecology

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Lactuca sativa var. capitata (commonly known as butterhead lettuce or Boston lettuce)


Hello, doctor.
Since I discovered cauliflower-like lesions in May and have been undergoing treatment, I would like to ask about my recent finding of a small lesion.
I have been using Aldara (Imiquimod) for four days, and the lesion has started to regress.
The inflammation has also improved.
Should I continue using Aldara? Yesterday, I applied Aldara to a previously affected area (which has healed), and today there is slight inflammation.
Currently, there are no lesions, but I am concerned about a potential recurrence.
I read online that Aldara only reacts when applied to skin with the virus.
Is this statement correct? I would appreciate your guidance.
Thank you.

Xiao Jie, 20~29 year old female. Ask Date: 2016/10/01

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, there are currently no lesions, so there should be no need to apply Lede Mei.
Wishing you good health.

Reply Date: 2016/10/01

More Info


LedaMed, which contains the active ingredient imiquimod, is a topical medication commonly used for the treatment of genital warts (condylomata acuminata) caused by human papillomavirus (HPV). It works by stimulating the immune system to fight the virus, leading to the destruction of the warts. The medication is typically applied directly to the affected area and is known for its effectiveness in reducing the size and number of warts.

In your case, since you have been using LedaMed for four days and have noticed a reduction in the lesions, it is a positive sign that the treatment is working. However, the decision to continue using LedaMed should be based on a few considerations:
1. Duration of Treatment: LedaMed is usually prescribed for a specific duration, often up to 16 weeks, depending on the severity and extent of the warts. If your healthcare provider has recommended a specific treatment plan, it’s important to follow that guidance.

2. Application on Healed Skin: You mentioned applying LedaMed on previously affected areas that have healed. While it is true that LedaMed is most effective on active lesions, applying it to healed skin can sometimes lead to irritation or inflammation, as you have experienced. It is generally advisable to apply the medication only to areas with visible warts or lesions. If there are no active lesions, it may not be necessary to continue applying the medication to those areas.

3. Monitoring for Recurrence: Genital warts can recur even after successful treatment. It is essential to monitor the treated areas for any new lesions. If you notice any new growths, it would be prudent to consult your healthcare provider for further evaluation and possible re-treatment.

4. Consulting Your Healthcare Provider: Since you are experiencing slight inflammation after applying LedaMed to a healed area, it would be wise to discuss this with your healthcare provider. They can assess whether you should continue treatment and provide recommendations tailored to your specific situation.

5. Understanding the Mechanism: The statement you read about LedaMed only being effective on skin with the virus is partially correct. While the medication is designed to target areas affected by HPV, it can also cause localized immune responses that may lead to irritation in previously affected areas. Therefore, it is crucial to apply it only as directed and to avoid unnecessary application to healed skin.

In summary, while LedaMed is an effective treatment for genital warts, its use should be carefully monitored, especially when applied to previously affected areas. If you have any concerns about the treatment or notice any adverse effects, it is best to consult your healthcare provider for personalized advice. They can help determine the best course of action, whether that involves continuing treatment, adjusting the application method, or exploring alternative therapies if necessary.

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