Syphilis Recurrence or Reinfection: Your Risks and Options - Urology

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Syphilis recurrence or reinfection?


Background summary: The individual is HIV positive and has been well-controlled on medication.
They received the hepatitis B vaccine about one to two months ago and had a syphilis infection approximately one to two years ago, with a recent syphilis titer of 24 two months ago.
Recently, they have noticed a suspicious red spot on the soles of their feet and palms, along with some genital symptoms.
Three months ago, they engaged in unprotected sexual intercourse, but the partner insists they do not have any sexually transmitted infections.

Question: Is it possible that this is a recurrence of syphilis, or is the likelihood of reinfection greater? I feel embarrassed to return to my original HIV doctor for syphilis treatment.
Can I seek treatment for this at another hospital? If I receive treatment from a different doctor, would my original doctor be able to track the changes in my syphilis titers and notice something is off? I apologize for the confusion in my thoughts.
Thank you, doctor.

Ao nao xue bu hui, 30~39 year old female. Ask Date: 2016/10/02

Dr. Sun Hongshun reply Urology


Hello, it sounds like there is a significant chance of syphilis.
As for new infections or recurrences, it is uncertain.
Since your immune system is relatively weak, please take extra precautions to protect yourself.
Healthcare providers genuinely care about your well-being, and I believe your health is their top priority.
Please continue your treatment with your original infectious disease specialist.
Wishing you safety and health.

Reply Date: 2016/10/02

More Info


Syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum, can present significant challenges, especially for individuals with underlying conditions such as HIV. Understanding the risks of recurrence or reinfection is crucial for managing your health effectively.

Given your history of syphilis and recent unprotected sexual encounters, it is essential to consider both the possibility of a recurrence of syphilis and the risk of reinfection. Recurrence typically refers to the reactivation of a previously treated infection, while reinfection occurs when a person contracts the infection again after successful treatment. In your case, if you have been treated adequately for syphilis in the past, the likelihood of recurrence is generally low. However, if you have engaged in unprotected sexual activity with a partner who may have syphilis, reinfection is a significant concern.

The symptoms you describe, such as the appearance of red spots on your palms and soles, could potentially indicate a new syphilis infection, especially if they are accompanied by other symptoms like sores or rashes. It is important to consult a healthcare provider for a thorough evaluation, including serological testing to determine your current syphilis status. Tests such as the Rapid Plasma Reagin (RPR) or the Venereal Disease Research Laboratory (VDRL) test can help assess whether you have an active syphilis infection.

Regarding your concerns about seeking treatment, it is entirely appropriate to visit another healthcare provider for syphilis treatment. You have the right to seek care from any qualified medical professional, and they can provide the necessary treatment and follow-up. If you choose to see a different doctor, it is advisable to inform them of your medical history, including your previous syphilis diagnosis and treatment. This information will help them understand your situation better and provide appropriate care.

Moreover, if your original healthcare provider is involved in your HIV treatment, they can still monitor your syphilis status through regular follow-ups and testing, even if you receive treatment from another doctor. Communication between healthcare providers is essential for comprehensive care, and they can share relevant information to ensure continuity of care.

In terms of lifestyle modifications, practicing safe sex is crucial to prevent both syphilis and other sexually transmitted infections (STIs). Using condoms consistently and correctly can significantly reduce your risk of reinfection. Additionally, regular STI screenings are advisable, especially for individuals with HIV, as they are at a higher risk for other infections.

In conclusion, while the symptoms you are experiencing could indicate a new syphilis infection, it is essential to consult a healthcare provider for accurate diagnosis and treatment. You have the option to seek care from another provider, and it is vital to maintain open communication about your health history. Taking proactive steps in your sexual health can help mitigate risks and ensure better health outcomes.

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