Mitral Valve Prolapse with Regurgitation: Concerns for Heart Health - Cardiology

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Mitral valve prolapse with mitral regurgitation and tricuspid regurgitation, associated with autoimmune disease?


Hello Doctor, I would like to ask about my condition.
I have mitral valve prolapse (MVP) with associated mitral regurgitation (MR) and tricuspid regurgitation (TR).
In my last echocardiogram report, the physician made the following diagnoses: * Interpretation: 1.
MVP (anterior mitral leaflet) 2.
MR (+), TR (+) 3.
Normal E/A ratio 4.
Normal left ventricular (LV) systolic function 5.
No chamber dilation.
IMP: MVP (anterior mitral leaflet).
Explanation: * Measurement: 2D mode 1.
IVS: 7.7 mm 2.
LVPW: 7.7 mm 3.
LVEDD: 36.4 mm 4.
LVESD: 22.5 mm 5.
AoD: 25.3 mm 6.
LAD: 26.2 mm 8.
LVEF: 69% 9.
EPSS: 3.0 mm 10.
E/A: 0.94 * Valve: MV: Normal AV: Normal TV: Normal PV: Normal * Wall motion: Normal * MR: I * AR: Nil * TR: I PG: 25 mmHg * PR: Nil * IVC: mm normal.

I would like to know if my TR: I PG: 25 mmHg requires special attention? Because in the past two days, I suddenly woke up gasping for air from my sleep, and I have had a persistent tightness and stabbing pain in my left chest that lasts for several hours, but I do not have sleep apnea, so I find it puzzling! Additionally, I have autoimmune thyroid disease and antiphospholipid syndrome, and I am currently taking Bokey and quinine.
This month, in order to increase my chances of pregnancy, I also started taking Lovenox, but the chest pain is very uncomfortable, and I am worried about the burden on my heart during future pregnancies.
My father has heart disease; he mentioned that he started having cardiac hypertrophy in his 30s, and I am 30 years old this year, so I am concerned that I might end up like him.

Winnie Wu, 30~39 year old female. Ask Date: 2016/10/05

Dr. He Dongjin reply Cardiology


Hello, the report shows normal TR: I PG: 25 mmHg, which is not a concern.
Just monitor it; the symptoms should not be directly related to the above examination.
Will I have heart disease? Don't worry about the future; no one knows, and worrying excessively is unhelpful.
Changhua Hospital cares about you.

Reply Date: 2016/10/05

More Info


Mitral Valve Prolapse (MVP) with associated mitral regurgitation (MR) and tricuspid regurgitation (TR) can raise several concerns regarding heart health, especially in the context of your symptoms and family history. Let’s break down the findings from your echocardiogram and your current health concerns.


Understanding Your Echocardiogram Results
1. Mitral Valve Prolapse (MVP): This condition occurs when the mitral valve does not close properly, which can lead to regurgitation. In your case, the report indicates MVP with mild MR. This means that while the valve is not functioning perfectly, the degree of regurgitation is not severe.

2. Tricuspid Regurgitation (TR): The report indicates mild TR with a pressure gradient (PG) of 25 mmHg. Mild TR is common and often does not require treatment unless it becomes more severe or is associated with significant symptoms.

3. Normal Left Ventricular (LV) Function: Your LV systolic function is reported as normal (LVEF of 69%), which is a positive sign. This indicates that your heart is pumping effectively, which is crucial in managing any valvular heart disease.

4. No Chamber Dilation: The absence of chamber dilation suggests that your heart is not under undue stress, which is a good sign in the context of MVP and regurgitation.


Symptoms of Concern
You mentioned experiencing sudden shortness of breath while sleeping and persistent chest tightness and pain. These symptoms can be concerning, especially in the context of your family history of heart disease. While MVP and mild regurgitation are often benign, the presence of new or worsening symptoms warrants further evaluation.

Family History and Risk Factors
Given your father's history of heart disease and hypertrophy at a young age, it is understandable to be concerned about your own heart health. Family history is a significant risk factor for cardiovascular disease, and it is essential to monitor your heart health closely.


Autoimmune Conditions and Pregnancy Considerations
Your autoimmune thyroid condition and antiphospholipid syndrome add complexity to your health profile. These conditions can influence cardiovascular health and may increase the risk of complications during pregnancy. The medications you are taking, including Bokey and Quinine, should be discussed with your healthcare provider, especially as you are considering pregnancy.

Recommendations
1. Consult Your Cardiologist: Given your symptoms of chest pain and shortness of breath, it is crucial to discuss these with your cardiologist. They may recommend further testing, such as a stress test or Holter monitor, to evaluate your heart's function under stress and to rule out any arrhythmias or other underlying issues.

2. Monitor Symptoms: Keep a detailed record of your symptoms, including when they occur, their duration, and any associated activities. This information can be invaluable for your healthcare provider in assessing your condition.

3. Consider a Comprehensive Evaluation: Given your family history and current symptoms, a comprehensive cardiovascular evaluation may be warranted. This could include imaging studies or even a referral to a specialist in congenital or valvular heart disease.

4. Pregnancy Planning: If you are considering pregnancy, it is essential to have a preconception consultation with both your cardiologist and an obstetrician familiar with high-risk pregnancies. They can help you understand the implications of your heart condition and autoimmune disorders on pregnancy and guide you on how to optimize your health before conception.

5. Lifestyle Modifications: Maintaining a heart-healthy lifestyle is crucial. This includes a balanced diet, regular exercise (as advised by your doctor), and avoiding smoking or excessive alcohol consumption.

In conclusion, while MVP and mild regurgitation are often manageable, your symptoms and family history necessitate a proactive approach to monitoring and managing your heart health. Regular follow-ups with your healthcare provider are essential to ensure that any changes in your condition are addressed promptly.

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