High SGPT and SGOT Levels in a 16-Year-Old: What to Do Next? - Gastroenterology and Hepatology

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A 16-year-old with elevated SGPT (ALT) and SGOT (AST) levels?


Hello, doctor.
My son is in his first year of high school, and during a school health check, his SGPT was 78 and SGOT was 77.
He is 170 cm tall and weighs 76.5 kg, giving him a BMI of 26.38.
Both Hepatitis B tests came back negative.
Since he is still a student, I tried to make an appointment with a hepatobiliary specialist online but was refused due to his age.
I don't understand this situation.
Given these values, what would you recommend for seeking medical advice?

Guo Xiaojie, 10~19 year old female. Ask Date: 2016/10/04

Dr. Chen Shidian reply Gastroenterology and Hepatology


Hello, Miss.
You can schedule an appointment with the Pediatric Gastroenterology and Hepatology department, as it is often related to fatty liver, but we need to confirm this.
Changhua Hospital cares about your health.
Chen Shidian.

Reply Date: 2016/10/04

More Info


When faced with elevated SGPT (ALT) and SGOT (AST) levels in a 16-year-old, it is essential to approach the situation with careful consideration and appropriate medical guidance. SGPT and SGOT are enzymes found in the liver and other tissues, and elevated levels can indicate liver inflammation or damage. In your son's case, with SGPT at 78 and SGOT at 77, these values are indeed higher than the normal range, which typically should be below 40 U/L for both enzymes in adolescents.

First and foremost, it is crucial to understand the potential causes of elevated liver enzymes. Common reasons include viral hepatitis, fatty liver disease, alcohol consumption, certain medications, and metabolic disorders. Given that your son tested negative for Hepatitis B, this rules out one of the more common viral causes. However, other factors could still be at play.

Since your son is a student and likely has a busy lifestyle, it is worth considering his diet, exercise habits, and any medications or supplements he may be taking. A high BMI (26.38) suggests that he may be overweight, which can contribute to non-alcoholic fatty liver disease (NAFLD), a condition increasingly seen in adolescents. This condition is characterized by fat accumulation in the liver and can lead to elevated liver enzymes.

Regarding your difficulty in scheduling an appointment with a hepatologist due to your son's age, this can sometimes happen as certain specialists may have age restrictions or prefer to see patients through a pediatrician or family doctor first. It is advisable to consult with your primary care physician or a pediatrician who can evaluate your son's overall health, review his medical history, and possibly conduct further tests such as an ultrasound of the liver or additional blood tests to assess liver function and rule out other conditions.

In the meantime, here are some steps you can take to help manage your son's health:
1. Dietary Changes: Encourage a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Reducing the intake of processed foods, sugars, and saturated fats can help improve liver health.

2. Physical Activity: Aim for at least 60 minutes of moderate to vigorous physical activity most days of the week. Regular exercise can help manage weight and improve overall health.

3. Hydration: Ensure he stays well-hydrated, as adequate water intake is essential for liver function.

4. Avoid Alcohol and Drugs: Educate him on the importance of avoiding alcohol and recreational drugs, which can exacerbate liver issues.

5. Regular Monitoring: Keep track of his liver enzyme levels with follow-up blood tests as recommended by his healthcare provider.

6. Stress Management: Encourage practices that reduce stress, such as mindfulness, yoga, or other relaxation techniques.

In summary, while elevated SGPT and SGOT levels warrant further investigation, they are not uncommon in adolescents and can often be managed effectively with lifestyle changes and appropriate medical care. It is crucial to work closely with a healthcare provider to determine the underlying cause and develop a tailored plan for your son's health. If necessary, seek a referral to a specialist who can provide the appropriate care for his age group.

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