Morning Fatigue and Swelling: Managing Chemotherapy Side Effects - Internal Medicine

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I can't get out of bed in the morning..?


Hello, Doctor Wu.
I would like to ask about my mother, who has been taking chemotherapy medication, specifically Capecitabine, for the past two months.
She has gradually started experiencing some physical discomfort, including difficulty getting out of bed in the morning, swelling in her left hand and face, and slow wound healing.
We consulted her doctor, who mentioned that these symptoms might be due to the medication's effects, but also suggested that these side effects should not typically occur.
I researched online and found that it could potentially be related to kidney deficiency.
I have also tried to improve her diet to provide nourishment, but the symptoms seem to return after a day or two.
Could you please advise which specialty she should consult? Additionally, are there any specific foods or nutrients that could help improve her condition? Thank you!

Chen Kai-te, 30~39 year old female. Ask Date: 2016/10/06

Dr. Wu Hongjie reply Internal Medicine


Hello: Regarding the weakness caused by chemotherapy drugs, it is recommended that you consult with your original hematology-oncology physician or seek assistance from traditional Chinese medicine for support.
Wishing you all the best.

Reply Date: 2016/10/06

More Info


Managing side effects from chemotherapy can be a complex issue, especially when dealing with medications like Sutent (sunitinib), which is commonly used for certain types of cancer treatment. Your mother’s symptoms, including morning fatigue, swelling in her left hand and face, and slow wound healing, can indeed be related to the chemotherapy regimen she is undergoing.
Firstly, it’s important to understand that chemotherapy can have a wide range of side effects, which vary from person to person. Common side effects include fatigue, swelling (edema), and delayed wound healing, all of which can be exacerbated by the specific drugs used in treatment. In your mother’s case, the fatigue she experiences in the morning could be due to the cumulative effects of the chemotherapy, which can disrupt sleep patterns and overall energy levels.
The swelling she is experiencing, particularly in her left hand and face, may be a result of fluid retention, which can occur with certain chemotherapy agents. This fluid retention can be influenced by several factors, including kidney function, dietary sodium intake, and overall hydration status. It’s crucial to monitor her fluid intake and consider reducing sodium in her diet, as high sodium levels can exacerbate swelling.
Regarding her slow wound healing, chemotherapy can impair the immune system and reduce the body’s ability to heal. This is particularly concerning if she has any surgical wounds or injuries. It’s essential to ensure that she is receiving adequate nutrition, as certain vitamins and minerals play a critical role in wound healing. Nutrients such as vitamin C, zinc, and protein are particularly important. Foods rich in these nutrients include citrus fruits, nuts, seeds, lean meats, and legumes.

Given the symptoms you describe, it would be advisable to consult with her oncologist or a healthcare provider specializing in oncology. They can evaluate her symptoms in the context of her chemotherapy treatment and may consider adjusting her medication or providing supportive care to manage these side effects. Additionally, a referral to a dietitian who specializes in oncology could be beneficial. They can provide tailored dietary advice to help improve her nutritional status and potentially alleviate some of the side effects she is experiencing.

In terms of managing her symptoms at home, here are a few suggestions:
1. Hydration: Encourage her to drink plenty of fluids, but monitor her sodium intake to help manage swelling.


2. Diet: Focus on a balanced diet rich in fruits, vegetables, lean proteins, and whole grains. Foods high in antioxidants may help support her immune system.

3. Rest: Ensure she gets adequate rest and sleep. If fatigue is a significant issue, short naps during the day may help.

4. Gentle Exercise: If she is able, gentle exercises like walking or stretching can help improve circulation and reduce swelling.

5. Monitoring Symptoms: Keep a close eye on her symptoms and report any significant changes to her healthcare provider, especially if swelling worsens or if she experiences pain or discomfort.

6. Supportive Therapies: Some patients find relief from symptoms through complementary therapies such as acupuncture, massage, or meditation, but these should be discussed with her healthcare team to ensure they are safe and appropriate.

In summary, while some of the symptoms your mother is experiencing may be related to her chemotherapy treatment, it’s essential to have a thorough evaluation by her oncologist. They can provide the best guidance on managing these side effects and ensuring her overall well-being during her treatment.

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