Hair Loss: Should Women Use Minoxidil for Androgenetic Alopecia? - Dermatology

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Hello Doctor, I recently consulted a physician regarding my hair loss issue.
The doctor diagnosed me with early-stage androgenetic alopecia and recommended using Minoxidil 2% or 5% topical solution.
However, I also came across some information online stating that hair follicles have a limited number of growth cycles, and using Minoxidil may initially stimulate hair growth but could ultimately lead to premature follicle death.
Is this true? I am a female and cannot take oral medication.
Once I start using Minoxidil, I cannot stop.
I'm unsure whether I should proceed with the treatment.
Thank you, Doctor.

Bei Ka, 20~29 year old female. Ask Date: 2016/10/11

Dr. Wu Yuxin reply Dermatology


If you care a lot about your hair, it is still recommended to continue using it.

Reply Date: 2016/10/11

More Info


When it comes to treating androgenetic alopecia (commonly known as female pattern hair loss) in women, Minoxidil is one of the most widely recommended topical treatments. It is available in both 2% and 5% concentrations. Your doctor’s suggestion to use Minoxidil is consistent with current medical guidelines, as it has been shown to promote hair regrowth and slow down hair loss in women with this condition.

The concern you mentioned about hair follicles having a limited number of growth cycles is rooted in the biology of hair growth. Hair follicles do indeed go through cycles of growth (anagen), rest (telogen), and shedding (catagen). While it is true that excessive stimulation of hair follicles can potentially lead to premature exhaustion of their growth cycles, the evidence supporting this claim in the context of Minoxidil use is limited. Most studies indicate that Minoxidil can effectively prolong the anagen phase and promote hair regrowth without significantly harming the follicles.

It's important to understand that Minoxidil works by increasing blood flow to the hair follicles, which can help revitalize shrunken hair follicles, increase their size, and prolong the growth phase of hair. This is particularly beneficial for women experiencing androgenetic alopecia, as it can help counteract the effects of dihydrotestosterone (DHT), a hormone that contributes to hair thinning.

Regarding your concern about starting Minoxidil and the potential for dependency, it is true that once you begin using Minoxidil, it is generally recommended to continue its use to maintain the benefits. If you stop using it, any hair regrowth achieved may be lost, and hair loss may resume. This is a common aspect of many hair loss treatments, not just Minoxidil.

If you are unable to take oral medications due to health concerns or contraindications, topical Minoxidil remains a viable option. However, it is crucial to follow the instructions provided by your healthcare provider and to monitor your response to the treatment. If you experience any adverse effects, such as scalp irritation or unusual hair growth in unwanted areas, you should consult your doctor.

In summary, using Minoxidil for androgenetic alopecia in women is generally safe and effective. While there are concerns about the long-term effects on hair follicles, the benefits of using Minoxidil often outweigh these risks. If you have any lingering doubts or specific health concerns, it would be wise to discuss them with your healthcare provider, who can provide personalized advice based on your medical history and current condition.

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