Urinary protein and renal pathology?
1.
I am a diabetes patient.
In July of this year, my test results showed: creatinine 0.71, microalbumin (urine) 4.95, glomerular filtration rate 94.19, urine creatinine 132.06, microprotein/urine creatinine ratio 37.48, RBC (red blood cells) 6-10, WBC (white blood cells) 100-200, bacteria (+), and normal blood pressure.
My question is: 1.
Does this indicate kidney damage?
2.
The doctor prescribed me Synbot
The doctor mentioned that even though I do not have blood pressure issues, this medication can help treat urinary protein.
Is this true?
3.
The doctor only mentioned arranging a blood test and did not indicate a urine test.
On the morning of the test, I had sexual intercourse (with a condom).
Will this affect the urine test results?
4.
Will my diet prior to the test date affect the results of urinary protein?
OOO, 40~49 year old female. Ask Date: 2016/10/15
Dr. Li Xinyi reply Urology
Diabetes may be associated with kidney issues, leading to microalbuminuria.
Treatment for proteinuria should be beneficial.
Engaging in sexual activity may increase the risk of urinary tract infections, which can affect urine tests showing RBCs (red blood cells) at 6-10, WBCs (white blood cells) at 100-200, and bacteria (+).
What does this indicate? Since you are seeking medical attention, it is advisable to ask your attending physician for clarification on the spot; otherwise, relying on the internet can be time-consuming and unclear.
Reply Date: 2016/10/15
More Info
Understanding proteinuria and kidney disease in diabetic patients is crucial, especially given the increasing prevalence of diabetes and its complications. Your situation raises several important points regarding kidney function, the implications of proteinuria, and the management of diabetes.
1. Is this indicative of kidney damage?
Based on your lab results, particularly the presence of microalbumin in your urine (4.95 mg/dL), it suggests that there may be some degree of kidney impairment. In diabetic patients, microalbuminuria is often an early sign of diabetic kidney disease (DKD). The normal range for microalbuminuria is less than 30 mg/g creatinine. Your microalbumin/creatinine ratio (37.48) indicates that you are in the microalbuminuria range, which is a warning sign that your kidneys may be starting to be affected by diabetes. However, your creatinine level (0.71 mg/dL) and estimated glomerular filtration rate (eGFR) of 94.19 mL/min suggest that your kidney function is still within normal limits. It is essential to monitor these values regularly, as early intervention can help prevent the progression of kidney disease.
2. Does Enalapril help with proteinuria?
Enalapril, an ACE inhibitor, is commonly prescribed not only for hypertension but also for its renal protective effects in diabetic patients. Even if your blood pressure is normal, Enalapril can help reduce proteinuria and slow the progression of kidney disease. It does this by decreasing intraglomerular pressure, which can help protect the kidneys from damage caused by high blood sugar levels. Therefore, your doctor’s recommendation to use Enalapril is appropriate, as it can be beneficial in managing your kidney health.
3. Does sexual activity affect urine tests?
Engaging in sexual activity before a urine test can potentially influence the results, particularly if it leads to the introduction of bacteria into the urinary tract, which could cause a urinary tract infection (UTI). The presence of bacteria in your urine (as indicated by the positive bacteria result) and the elevated white blood cell count (100-200) could suggest a UTI, which might be exacerbated by recent sexual activity. It is advisable to inform your healthcare provider about this activity prior to testing, as it may necessitate a repeat urine test for accurate results.
4. Does diet affect urine protein results?
Yes, dietary factors can influence urine protein levels. High protein intake can temporarily increase protein levels in urine, so it is essential to maintain a balanced diet leading up to your tests. Additionally, factors such as hydration status, physical activity, and even stress can affect urine composition. It is advisable to follow any dietary recommendations provided by your healthcare team, especially those tailored for diabetic patients, to ensure accurate test results.
In summary, your lab results indicate the need for careful monitoring of your kidney function, particularly in the context of diabetes. The presence of microalbuminuria is a significant finding that warrants attention. Enalapril is a suitable medication for managing both blood pressure and proteinuria, and it is essential to maintain open communication with your healthcare provider regarding any factors that may affect your test results. Regular follow-ups and lifestyle modifications, including diet and exercise, will be crucial in managing your diabetes and protecting your kidney health.
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