Abnormal White Blood Cell Counts: What You Need to Know - Family Medicine

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Abnormal white blood cell count?


Hello Dr.
Liao: Recently, after a health check-up, I found that two values in the report were abnormal: Neutrophil percentage (Neu%) 28.5 (normal range: 40-75%) and Lymphocyte percentage (Lym%) 59.9 (normal range: 20-50%).
I did not have any cold or take any medication before the check-up.
Could you please advise if this indicates any areas of concern? I was wondering if it could be related to carrying the hepatitis B virus.
However, both values were normal in last year's check-up.
Thank you, Dr.
Liao!

Osborn, 30~39 year old female. Ask Date: 2016/10/27

Dr. Liao Yaopan reply Family Medicine


Hello, regarding your inquiry, the white blood cell count and differential should be interpreted together.
The classification of each type of white blood cell is presented as a percentage, totaling 100%.
Therefore, if you have any concerns, it is advisable to consult your family physician or seek an evaluation from a hematology specialist.
Changhua Hospital cares about you.

Reply Date: 2016/10/27

More Info


Understanding abnormal white blood cell counts is crucial for assessing your overall health and identifying potential underlying conditions. In your case, the report indicates a low percentage of neutrophils (28.5%, with a normal range of 40-75%) and a high percentage of lymphocytes (59.9%, with a normal range of 20-50%). These findings can provide insights into your immune system's status and potential health issues.

Neutrophils are a type of white blood cell that plays a vital role in fighting off infections, particularly bacterial infections. A low neutrophil count, or neutropenia, can make you more susceptible to infections. This condition can arise from various factors, including bone marrow disorders, autoimmune diseases, certain medications, and viral infections. In your case, since you mentioned that you have not experienced any recent illnesses or taken medications, it may be worth investigating further to determine the cause of the low neutrophil count.

On the other hand, lymphocytes are another type of white blood cell that is essential for the immune response, particularly in fighting viral infections and in the regulation of the immune system. An elevated lymphocyte count, or lymphocytosis, can occur due to several reasons, including viral infections, chronic inflammatory conditions, and certain types of leukemia. Given that your lymphocyte percentage is elevated, it may indicate a response to a viral infection or another underlying condition that warrants further evaluation.

Regarding your concern about hepatitis B, while chronic hepatitis B can affect white blood cell counts, it typically does not cause isolated changes in neutrophils and lymphocytes in the manner you described. However, if you have a history of hepatitis B, it would be prudent to discuss this with your healthcare provider, as they may recommend further testing to assess your liver function and the status of the virus.

It is also important to consider that laboratory values can fluctuate due to various factors, including stress, hydration status, and even the time of day the blood was drawn. Since your previous tests showed normal values, it may be beneficial to repeat the blood tests after a short period to see if the values normalize.

In summary, the abnormal white blood cell counts you are experiencing warrant further investigation. It is advisable to consult with a hematologist or your primary care physician, who can evaluate your complete blood count in the context of your medical history, symptoms, and any other relevant tests. They may recommend additional tests, such as a peripheral blood smear or bone marrow biopsy, to rule out any serious conditions and to determine the underlying cause of your abnormal results.

In the meantime, maintaining a healthy lifestyle, including a balanced diet rich in vitamins and minerals, regular exercise, and adequate hydration, can support your immune system. If you experience any symptoms such as fever, recurrent infections, or unusual bruising or bleeding, seek medical attention promptly. Your health is paramount, and staying proactive about your well-being is essential.

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