Kidney Function: Is Your GFR Too Low? - Internal Medicine

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Kidney problems


Hello, doctor! I recently received my health check report, which shows a serum creatinine level of 1.23 mg/dL and a glomerular filtration rate (GFR) of 77.51.
There were no signs of hematuria or proteinuria.
I would like to ask if my GFR is considered low, as I have heard that many people have a GFR above 90.
Would drinking more water help improve this issue? I appreciate your assistance! Thank you.

Niming, 20~29 year old female. Ask Date: 2016/11/07

Dr. Wang Weijie reply Internal Medicine


Hello: In healthy individuals without proteinuria, a glomerular filtration rate (eGFR) greater than 80 ml/min is considered normal.
If there is foamy urine, it may indicate proteinuria, and it is recommended to follow up with a nephrologist.
Chronic kidney disease is classified into five stages based on the eGFR: Stage 1 - Normal kidney function with microalbuminuria (eGFR 90-120 ml/min), Stage 2 - Mild chronic kidney disease (eGFR 60-90 ml/min), Stage 3 - Moderate chronic kidney disease (eGFR 30-60 ml/min), Stage 4 - Severe chronic kidney disease (eGFR 15-30 ml/min), and Stage 5 - End-stage renal disease (eGFR 0-15 ml/min).
Early-stage kidney disease may not present obvious symptoms.
If individuals experience the following symptoms, they should seek medical attention promptly, especially those with hypertension, hyperlipidemia, heart disease, or diabetes.
It is important to remember the mnemonic for kidney disease symptoms: "Foam, Water, High, Anemia, Fatigue": Foam: Presence of fine bubbles in urine that last more than 30 seconds; Water: Swelling in the lower extremities when pressed; High: Hypertension; Anemia: Unexplained anemia; Fatigue: Frequent feelings of tiredness and weakness.
Wishing you safety and health.
Sincerely, Dr.
Wang Wei-Jie, Attending Physician, Nephrology Department, Taoyuan Hospital, Ministry of Health and Welfare.

Reply Date: 2016/11/07

More Info


Understanding kidney function is crucial for maintaining overall health, especially as we age. Your recent health check results indicate a serum creatinine level of 1.23 mg/dL and an estimated Glomerular Filtration Rate (eGFR) of 77.51 mL/min/1.73 m². To assess whether your eGFR is too low, it's essential to understand what these numbers mean in the context of kidney health.

The eGFR is a key indicator of kidney function, estimating how well your kidneys filter blood. Normal eGFR values typically range from 90 to 120 mL/min/1.73 m², with values below 60 mL/min indicating potential kidney disease. Your eGFR of 77.51 suggests that your kidney function is mildly decreased but not at a level that would typically raise immediate concern. It's important to note that eGFR can vary based on factors such as age, sex, and muscle mass. As people age, eGFR tends to decline naturally, and a value between 60 and 89 can be considered normal for older adults.

Your serum creatinine level of 1.23 mg/dL is slightly elevated, which can be a sign of reduced kidney function. However, it is essential to interpret this value in conjunction with your eGFR. Since you do not have signs of proteinuria or hematuria (blood in urine), this further suggests that your kidneys are functioning relatively well despite the slight elevation in creatinine.

Regarding your question about hydration, drinking adequate water is indeed beneficial for kidney health. Proper hydration helps the kidneys filter waste from the blood more effectively and can prevent the formation of kidney stones. However, while increasing your water intake can support kidney function, it is unlikely to significantly improve your eGFR if there are underlying issues affecting kidney health.
It's also important to consider lifestyle factors that can impact kidney function. Maintaining a balanced diet low in sodium and processed foods, managing blood pressure and blood sugar levels, and avoiding over-the-counter medications that can harm the kidneys (like NSAIDs) are all crucial steps. Regular monitoring of kidney function through blood tests is advisable, especially if you have risk factors such as hypertension, diabetes, or a family history of kidney disease.

In summary, while your eGFR of 77.51 mL/min/1.73 m² indicates a mild decrease in kidney function, it is not critically low. Regular follow-ups with your healthcare provider are essential to monitor your kidney health over time. They may recommend further tests or lifestyle modifications based on your overall health status. Drinking plenty of water and maintaining a healthy lifestyle will support your kidney function and overall health. If you have any concerns or experience symptoms such as swelling, fatigue, or changes in urination, be sure to consult your healthcare provider for personalized advice.

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