Gallbladder Polyps: Risks, Symptoms, and Surgical Options - Gastroenterology and Hepatology

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Cholecystectomy


Hello Doctor, during today's employee health check, an abdominal ultrasound revealed a 0.4 x 0.7 cm polyp at the fundus of the gallbladder, which was not detected in last year's ultrasound.
Other blood test results are as follows: CEA and CA 19-9 are normal; CA 72-4 was 17.4 and then retested at 7.9 two days later (normal value < 6.4).
Earlier this year, I underwent gastroscopy and colonoscopy, both of which were normal, with only mucosal damage caused by gastroesophageal reflux.
I have the following questions: 1.
The gastroscopy was normal, but CA 72-4 is above the normal range.
Is this related to gastroesophageal reflux or the gallbladder polyp? 2.
There was no polyp detected last year, but now there is one after a year.
My grandfather passed away from related diseases, and this polyp makes me very fearful and anxious.
If I do not want to endure the ongoing monitoring, can I have my gallbladder removed? I appreciate your response.

Dom, 20~29 year old female. Ask Date: 2016/11/07

Dr. Chen Qifeng reply Gastroenterology and Hepatology


CA72-4 is a marker that has high sensitivity but low specificity; it can be elevated even in cases of gastric inflammation.
As for gallbladder polyps, they are generally not related.
It is usually recommended to follow up every six months, and intervention is only considered if the polyp is larger than one centimeter.
If you wish to proceed with surgery earlier, you will need a surgeon who is willing to perform the procedure.

Reply Date: 2016/11/07

More Info


When it comes to gallbladder polyps, understanding the risks, symptoms, and surgical options is crucial for making informed decisions about your health. Based on your recent ultrasound findings of a gallbladder polyp measuring 0.4 x 0.7 cm, it’s important to consider several factors before deciding on a course of action.


Understanding Gallbladder Polyps
Gallbladder polyps are growths that protrude from the lining of the gallbladder. They are often discovered incidentally during imaging studies, such as ultrasounds. Most gallbladder polyps are benign and do not cause symptoms. However, certain types of polyps, particularly those larger than 1 cm, have a higher risk of being malignant (cancerous) and may warrant surgical intervention.


Risks and Symptoms
The majority of gallbladder polyps are asymptomatic, meaning they do not produce noticeable symptoms. However, if a polyp grows larger or if there are other concerning features (such as a rapid increase in size or associated gallstones), symptoms may arise, including abdominal pain, nausea, or jaundice.
In your case, the polyp is relatively small, and given that it was not present in last year's ultrasound, it is likely a new finding. The risk of malignancy in polyps less than 1 cm is generally low, but it is essential to monitor them over time.

CA72-4 Levels and Their Implications
Regarding your elevated CA72-4 levels, it’s important to note that this marker can be associated with various conditions, including gastrointestinal cancers. However, it is not specific to gallbladder polyps or gastroesophageal reflux disease (GERD). Elevated CA72-4 levels may indicate inflammation or other benign conditions, but they can also raise concerns about malignancy. It would be prudent to discuss these results with your healthcare provider to determine if further evaluation is necessary.


Surgical Options
If you are feeling anxious about the presence of the polyp, it is understandable to consider surgical options. Cholecystectomy, or gallbladder removal, is a common procedure for patients with symptomatic gallbladder disease or concerning polyps. However, the decision to proceed with surgery should be based on a thorough discussion with your healthcare provider, considering factors such as:
1. Size and Characteristics of the Polyp: Polyps larger than 1 cm or those with suspicious features may require surgical removal.

2. Family History: Given your family history of related diseases, this may influence your decision-making process.

3. Personal Health and Symptoms: If you are experiencing symptoms or have significant anxiety regarding the polyp, these factors should be taken into account.


Monitoring and Follow-Up
If you choose not to undergo surgery at this time, regular monitoring through ultrasound examinations is typically recommended. This allows for the assessment of any changes in the size or characteristics of the polyp over time. Generally, follow-up ultrasounds are performed every 6 to 12 months for small polyps.


Conclusion
In summary, while your gallbladder polyp is currently small and likely benign, the decision to monitor or surgically remove the gallbladder should be made collaboratively with your healthcare provider. They can help you weigh the risks and benefits based on your specific situation, including your anxiety about the polyp and your family history of related diseases. Regular follow-up and open communication with your healthcare team will be key in managing your health moving forward.

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