Prolonged Symptoms of Gastroesophageal Reflux Disease - Gastroenterology and Hepatology

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The symptoms of gastroesophageal reflux disease (GERD) have persisted for a long time?


Hello doctor, I had an upper gastrointestinal endoscopy at the age of 21, which revealed significant gastroesophageal reflux disease (GERD).
I sought the procedure because I was experiencing persistent discomfort in my stomach, sometimes radiating to my left flank or the xiphoid process.
The doctor prescribed proton pump inhibitors (PPIs) and other medications, which helped, and I didn't have issues for a long time.
Occasionally, I experienced relapses and would get more medication.
However, starting in mid-August of this year, my symptoms have returned.
I went for a follow-up and received PPIs again, but this time it's strange because I don't have nausea, bloating, or heartburn.
Instead, I have persistent discomfort either in the xiphoid area or the left flank, alternating between the two.
This has been ongoing for quite some time now, and I'm unsure if it has developed into another issue.
My diet hasn't completely improved...
Would completely avoiding certain foods resolve this? The doctor mentioned that I have a relaxed lower esophageal sphincter.

You, 20~29 year old female. Ask Date: 2016/11/08

Dr. Chen Shidian reply Gastroenterology and Hepatology


Hello, sir.
You can either see a doctor first for an examination or start medication right away; there's no need to worry.
Changhua Hospital cares about your health.
Chen Shidian.

Reply Date: 2016/11/08

More Info


Gastroesophageal reflux disease (GERD) is a chronic condition that occurs when stomach acid or, occasionally, stomach content flows back into the esophagus. This backflow, known as reflux, can irritate the lining of the esophagus and lead to various symptoms. Your history of GERD, along with the recent resurgence of symptoms, raises several important considerations.

Firstly, it is crucial to understand that GERD can manifest in various ways. While many patients experience classic symptoms such as heartburn, regurgitation, and nausea, others may present with atypical symptoms. In your case, the absence of typical symptoms like nausea and heartburn, coupled with persistent discomfort in the sternum and left flank, suggests that your GERD may be presenting differently this time. This could indicate a few possibilities:
1. Esophageal Motility Disorders: Sometimes, the esophagus may not function properly, leading to symptoms that mimic GERD. Conditions such as esophageal spasms or achalasia can cause chest pain and discomfort without the typical reflux symptoms.

2. Visceral Hyperalgesia: This is a condition where the nerves in the gastrointestinal tract become overly sensitive, leading to pain and discomfort even in the absence of significant reflux or damage.

3. Functional Dyspepsia: This is a term used to describe symptoms of indigestion that have no clear cause. It can include bloating, discomfort, and pain, which may overlap with your current symptoms.

4. Complications of GERD: Chronic GERD can lead to complications such as esophagitis, Barrett's esophagus, or even strictures, which could cause discomfort and pain.

Regarding your dietary habits, while it is essential to avoid known triggers such as spicy foods, caffeine, alcohol, and large meals, simply eliminating these foods may not be sufficient. A comprehensive approach that includes:
- Smaller, more frequent meals: This can help reduce the volume of stomach contents and decrease the likelihood of reflux.

- Elevating the head of the bed: This can help prevent nighttime symptoms by utilizing gravity to keep stomach contents from flowing back into the esophagus.

- Maintaining a healthy weight: Excess weight can increase abdominal pressure and exacerbate reflux symptoms.

You mentioned that your doctor indicated a possible loosening of the lower esophageal sphincter (LES). This is a common issue in GERD patients and can lead to increased reflux. If lifestyle modifications and medications (like PPIs) are not providing relief, further evaluation may be warranted. This could include:
- Esophageal pH monitoring: This test measures the amount of acid in the esophagus and can help determine if your symptoms correlate with acid reflux.

- Esophageal motility studies: These tests assess how well the esophagus is functioning and can identify motility disorders.

In conclusion, while dietary changes are important, they should be part of a broader management strategy that includes medication adherence and possibly further diagnostic testing. If your symptoms persist or worsen, it is crucial to follow up with your healthcare provider for a comprehensive evaluation and tailored treatment plan. Your health and comfort are paramount, and addressing these symptoms early can prevent complications down the line.

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