Elevated White Blood Cell Count and Its Health Implications - Internal Medicine

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Increasing white blood cell count, hypertension, anemia..?


I have been diagnosed with hypertension and frequently experience palpitations, anemia, shortness of breath, chest tightness, chest pain, headaches, and hypoglycemia.
Additionally, I experience left shoulder pain during exercise, and my entire body aches in the morning when it's cold.
I am currently a freshman in college, and our school conducts health checks for us.
Since I was in high school, my health check reports have consistently shown elevated white blood cell counts, with each subsequent count increasing by 2000 to 3000.
My most recent count was 18,352.
Could you please advise if there is any issue with this?

Xiao Hei, 10~19 year old female. Ask Date: 2016/11/16

Dr. Hong Yuanbin reply Internal Medicine


Hello, it is important to first understand if you have been ill a few days prior to the blood test, with the most common illnesses being a cold or gastroenteritis.
If so, it is likely due to an acute infection, and usually, your results will return to normal after a few days.
If not, the elevated white blood cell count is indeed abnormal, and I recommend visiting a hospital for a detailed examination.
Considering your other symptoms and your young age, it may be necessary to check your blood sugar, lipid levels, heart, lungs, and bone marrow to make an accurate diagnosis.
Thank you for your question.

Reply Date: 2016/11/16

More Info


Elevated white blood cell (WBC) counts, also known as leukocytosis, can be a significant indicator of various underlying health conditions. In your case, the consistent increase in your WBC count, reaching a notably high level of 18,352, warrants careful consideration and further investigation.
White blood cells are crucial components of the immune system, responsible for defending the body against infections and foreign invaders. The normal range for WBC counts typically falls between 4,000 and 11,000 cells per microliter of blood. When the count exceeds this range, it can indicate several potential issues, including infections, inflammation, stress responses, or more serious conditions such as blood disorders or malignancies.

Given your medical history of hypertension, palpitations, anemia, shortness of breath, chest discomfort, and pain during physical activity, it is essential to approach this situation holistically. The combination of elevated WBC counts and your symptoms could suggest an underlying inflammatory process or chronic stress response. Conditions such as chronic infections, autoimmune diseases, or even stress-related disorders can lead to elevated WBC counts.
Moreover, the increase in your WBC count over time, particularly if it is rising by 2,000 to 3,000 cells each time, is concerning. This trend may indicate a persistent underlying issue that needs to be addressed. It is also important to consider that certain medications, physical stress, or even emotional stress can contribute to elevated WBC counts.
In your case, the symptoms you are experiencing—such as chest pain, difficulty breathing, and shoulder pain—should not be overlooked. These could be indicative of cardiovascular issues, especially given your history of high blood pressure. It is crucial to discuss these symptoms with a healthcare provider who can perform a comprehensive evaluation, including a thorough physical examination and possibly additional tests such as imaging studies or referrals to specialists.

Anemia, which you mentioned, can also complicate your situation. It can lead to fatigue and exacerbate feelings of weakness, which may contribute to your overall discomfort. The relationship between anemia and elevated WBC counts can be complex, as the body may increase WBC production in response to various stressors, including low oxygen levels due to anemia.

In summary, your elevated WBC count, particularly in conjunction with your other symptoms, should prompt further investigation. It is advisable to consult with a healthcare provider, preferably a hematologist or an internist, who can assess your complete blood count (CBC) results in the context of your overall health. They may recommend additional tests, such as a bone marrow biopsy or specific blood tests, to rule out conditions like leukemia or other hematological disorders.

In the meantime, maintaining a healthy lifestyle, managing stress, and ensuring proper hydration and nutrition can support your overall health. Regular follow-ups with your healthcare provider will be essential in monitoring your condition and addressing any emerging health concerns. Remember, early intervention can often lead to better outcomes, so do not hesitate to seek medical advice.

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