Managing Schizophrenia: Medication Adherence and Dosage Concerns - Psychiatry

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Hello, doctor. My uncle, Huang, has schizophrenia and is your patient?


Hello, doctor.
My uncle, Huang, has schizophrenia and is your patient.
He is currently taking a considerable amount of psychiatric medication.
He is 61 years old, and I have his medication bag from when he was 57, which is about four years ago.
The prescription from January 2, 2014, was for Sulpiride, to take three tablets at bedtime.
The prescription from October 20, 2014, was for Risperidone, to take four tablets each in the morning and at bedtime.
This year, on March 28, 2016, he was prescribed Olanzapine, to take two tablets in the morning and at bedtime.
Currently, there are still many Olanzapine tablets left at home, as well as some Risperidone and Sulpiride, but there are fewer Risperidone and Sulpiride tablets remaining.
However, he has not been taking his medication regularly, so there is still a lot left.

My questions are: Can we help him reduce his medication? Is it safe for him to take medication that is two or three years old? Will he recover from this illness? He seems to have taken Risperidone before, but since there are many Olanzapine tablets left, I have been giving him Olanzapine, and he still hasn't finished them.
Is this acceptable?

Huang Shaojun, 20~29 year old female. Ask Date: 2016/11/17

Dr. Wu Enliang reply Psychiatry


Hello Mr.
Huang: *Can we reduce his medication? No, do not reduce the medication; we will reassess at the next follow-up appointment.* Can he take the medication from two or three years ago? No, do not take medication from two or three years ago; the quality of the medication may be compromised.
Please return it to our pharmacy for proper disposal next time.* Will he recover from this condition? This is a chronic illness that requires long-term medication management; otherwise, it will worsen.* He seems to have taken Risperidone before, but I see there are still many tablets of Seroquel left, so I have been giving him Seroquel.
Is that okay? It is best to continue with the current medication and not to use any old prescriptions (Please remember, to protect the patient's and your own privacy, do not provide full names directly next time).

Reply Date: 2016/11/17

More Info


Managing schizophrenia effectively requires a comprehensive approach that includes medication adherence, dosage management, and regular monitoring by healthcare professionals. Your uncle's situation, as you've described, raises several important considerations regarding his treatment regimen.

Firstly, it's crucial to understand that schizophrenia is a chronic mental health disorder that often necessitates long-term treatment with antipsychotic medications. These medications can help manage symptoms such as delusions, hallucinations, and disorganized thinking. However, adherence to the prescribed medication schedule is vital for achieving optimal therapeutic outcomes. In your uncle's case, it appears that he has not been consistently taking his medications, which can lead to a resurgence of symptoms and potential exacerbation of his condition.

Regarding the medications he has been prescribed, it is essential to consult with his psychiatrist or healthcare provider before making any changes. Medications like Risperidone (理思必妥) and Olanzapine (思特寧) have specific dosing guidelines and can have varying effects based on individual patient factors, including age, weight, and overall health. The fact that he has leftover medications from previous prescriptions raises concerns about their efficacy and safety. Medications can lose potency over time, and using outdated prescriptions without professional guidance can be risky.

You mentioned the possibility of reducing his medication. This is a decision that should only be made in consultation with his psychiatrist. Abruptly stopping or reducing medication can lead to withdrawal symptoms or a relapse of schizophrenia symptoms. A healthcare provider can assess his current condition and determine whether a dosage adjustment is appropriate. They may also consider switching medications if the current ones are not effective or if he is experiencing intolerable side effects.

In terms of whether your uncle can take medications from two or three years ago, it is generally not advisable. Medications can change in formulation, and their effectiveness can diminish over time. Additionally, the risk of side effects may increase if medications are not taken as prescribed. Therefore, it is crucial to have a healthcare professional evaluate his current medications and determine the best course of action.

As for the question of whether he will get better, schizophrenia is a complex disorder, and while many individuals can manage their symptoms effectively with the right treatment, it often requires ongoing support and adjustments to the treatment plan. Recovery is possible, but it typically involves a combination of medication, therapy, and support from family and friends.

In conclusion, I recommend that you encourage your uncle to see his psychiatrist for a thorough evaluation of his current medication regimen. Open communication with his healthcare provider is essential for managing his condition effectively. They can provide guidance on medication adherence, potential adjustments, and additional support resources that may be beneficial for him. Remember, managing schizophrenia is a collaborative effort that involves the patient, their family, and healthcare professionals working together to achieve the best possible outcomes.

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