Lymph node core needle biopsy diagnosis
Hello Dr.
Hu: Previously, I consulted you several times regarding the issue of enlarged lymph nodes in my neck, as I was concerned about the possibility of lymphoma.
Therefore, you performed a core needle biopsy (using an 18-gauge needle, taking four samples), but you mentioned that the diagnostic value of a core needle biopsy for lymphoma is not very high and recommended that I undergo an excisional biopsy of the entire lymph node for further examination.
Yesterday, I went to the hospital to hear the results of the core needle biopsy, and the doctor said I have Kikuchi disease, advising me to rest at home as it will resolve on its own.
May I ask, Dr.
Hu, if it is necessary for me to undergo further examinations? My neck lymph nodes are in a chain, sometimes they enlarge and sometimes they shrink, and I occasionally feel a bloated discomfort.
My body temperature has been slightly lower than before (which should be during the follicular phase after my menstrual period), typically ranging from 36.5 to 37.0 in the morning and evening, but it may rise to 37.5 in the afternoon.
I initially had abdominal pain and other digestive issues, which have improved somewhat, but I have started experiencing intermittent headaches over the past few days.
Thank you for your response, doctor.
c, 20~29 year old female. Ask Date: 2016/11/23
Dr. Hu Ziren reply Oncology
Hello, if it is Kikuchi disease, then it is best to rest and allow it to heal on its own.
Reply Date: 2016/11/23
More Info
Kikuchi disease, also known as Kikuchi-Fujimoto disease, is a rare, benign condition characterized by lymphadenopathy (swollen lymph nodes) and fever. It primarily affects young adults and is often self-limiting, meaning it typically resolves on its own without the need for aggressive treatment. The diagnosis is usually confirmed through a lymph node biopsy, which can reveal histological features such as necrotizing lymphadenitis.
In your case, the diagnosis of Kikuchi disease from the fine needle aspiration biopsy (FNAC) suggests that the lymphadenopathy you are experiencing is not due to malignancy, such as lymphoma, which is a common concern when lymph nodes are swollen. The fact that your doctor recommended rest and indicated that the condition would likely resolve on its own is consistent with the typical management of Kikuchi disease.
Regarding your symptoms, it is common for lymph nodes to fluctuate in size and tenderness, especially in cases of Kikuchi disease. The discomfort you describe, along with the mild fever, can be attributed to the inflammatory process associated with the disease. Your temperature readings, which range from 36.5 to 37.5 degrees Celsius, are generally within normal limits, although the slight elevation in the afternoon could be related to the underlying condition.
As for whether you need further testing, it is essential to consider a few factors:
1. Symptom Monitoring: If your symptoms are mild and you are not experiencing significant discomfort or additional concerning symptoms (such as severe headaches, persistent fever, or weight loss), it may not be necessary to pursue further invasive testing at this time. Regular follow-up with your healthcare provider is crucial to monitor your condition.
2. Persistent Symptoms: If your lymphadenopathy persists beyond a few weeks, worsens, or if you develop new symptoms (such as significant fatigue, night sweats, or unexplained weight loss), further evaluation may be warranted. This could include imaging studies or possibly a surgical excisional biopsy of the lymph node for a more definitive diagnosis.
3. Headaches and Other Symptoms: The intermittent headaches you mentioned could be unrelated to the Kikuchi disease, but they should be evaluated, especially if they are new or different from your usual headaches. Keeping a symptom diary can help your healthcare provider assess any patterns or triggers.
4. Follow-Up Care: Regular follow-up appointments with your healthcare provider are essential. They can assess your symptoms, perform physical examinations, and determine if additional tests are necessary based on your clinical status.
In summary, Kikuchi disease is generally a self-limiting condition that does not require aggressive treatment. However, close monitoring of your symptoms and regular follow-up with your healthcare provider are crucial to ensure that any changes in your condition are promptly addressed. If you have any concerns or if your symptoms change, do not hesitate to reach out to your doctor for further guidance.
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