Struggling with Persistent Penile Inflammation: Seeking Answers After Multiple Doctors - Urology

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Penile inflammation and ulcers have not improved after consulting five doctors. I am seeking assistance?


Hello doctor, previously I had severe ulcers on the surface of the glans, but for unknown reasons, I now only have inflammation.
Initially, there were still ulcers, but after undergoing stone surgery, they suddenly disappeared.
My treating physician is also unsure why this happened, but now there are no ulcers, just inflammation.
This doctor mentioned that a biopsy would be necessary, but he also said it would only determine if it is benign and would not identify the underlying cause of my condition.
Should I still proceed with the biopsy?
This doctor has prescribed three types of ointments, but none have been effective.
I then went to a laboratory where they diagnosed me with a yeast infection.
They used a swab method to check for inflammation; is this accurate? I researched online and found that Candida and yeast infections seem quite similar, but the laboratory report indicated that I do not have a Candida infection.
What should I do now? I have applied numerous ointments, but none seem to treat the so-called yeast infection.
I have consulted both urology and dermatology specialists, and there has been no significant relief of symptoms.
This condition has persisted for a year and a half.
Is there still hope for me?

ai, 20~29 year old female. Ask Date: 2016/11/28

Dr. Sun Hongshun reply Urology


Hello, I am very sorry to hear that you are experiencing such significant distress from this condition.
I would suggest the following: if there are long-term ulcers or inflammation, a dermatopathological biopsy may be necessary.
As for why this has persisted for so long, issues with the immune system could be a potential direction to explore.
Therefore, I recommend that you seek further diagnosis and treatment from the dermatology and immunology/rheumatology departments at a major hospital.
Wishing you good health.

Reply Date: 2016/11/28

More Info


Persistent penile inflammation can be a challenging condition to manage, especially when it has been ongoing for an extended period, as in your case. It sounds like you have already seen multiple specialists, including urologists and dermatologists, and have undergone various treatments without significant improvement. Let's break down your situation and explore potential next steps.


Understanding Your Condition
1. Chronic Inflammation: The inflammation you are experiencing could be due to several factors, including infections (like yeast infections), irritants, or underlying skin conditions. The fact that you had ulcers that resolved after your surgery but continued to have inflammation suggests that there may be an underlying issue that needs to be addressed.

2. Yeast Infection: You mentioned that a test indicated a yeast infection. While Candida (the yeast responsible for infections) can cause inflammation and irritation, it is essential to differentiate between a yeast infection and other potential causes of your symptoms. The fact that you did not test positive for Candida albicans but still have symptoms suggests that there may be another underlying issue.

3. Skin Conditions: Conditions such as lichen sclerosus, lichen planus, or psoriasis can cause chronic inflammation and may not respond well to topical antifungal treatments. A biopsy, as suggested by your doctor, can help rule out these conditions and provide more information about the nature of the inflammation.


Next Steps
1. Consider the Biopsy: While a biopsy may not provide a definitive answer regarding the cause of your inflammation, it can help rule out serious conditions and confirm whether the inflammation is benign. If your doctor believes it is necessary, it may be worth proceeding with the biopsy to gain more insight.

2. Review Treatment Options: Since the topical treatments you have tried have not been effective, it may be time to discuss alternative therapies with your healthcare provider. This could include:
- Oral Antifungals: If a yeast infection is suspected, oral antifungal medications may be more effective than topical treatments.

- Corticosteroids: If inflammation is significant, a topical corticosteroid may help reduce inflammation and discomfort.

- Immunomodulators: In cases where inflammatory skin conditions are suspected, medications that modulate the immune response may be beneficial.

3. Follow-Up Testing: If the yeast infection was diagnosed through a swab, ensure that the method used was appropriate for detecting yeast. Sometimes, cultures can yield false negatives, and a different testing method may be warranted.

4. Lifestyle Modifications: Consider any potential irritants in your daily life that could be contributing to the inflammation. This includes soaps, detergents, or even certain fabrics. Maintaining good hygiene and avoiding irritants can help manage symptoms.

5. Seek a Second Opinion: If you feel that your current healthcare providers are not addressing your concerns adequately, consider seeking a second opinion from a specialist who focuses on chronic inflammatory conditions or a dermatologist with experience in genital skin disorders.


Conclusion
Chronic penile inflammation can be complex and multifactorial. It is crucial to work closely with your healthcare providers to explore all potential causes and treatment options. While it may feel discouraging after a long duration of symptoms, there are still avenues to pursue that may lead to relief. Don't hesitate to advocate for yourself and seek further evaluations or treatments that may help improve your condition.

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