Bladder Overactivity: When Antibiotics Are Not Needed - Urology

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Overactive bladder


Hello, Dr.
Du.
Recently, for the past two weeks, I have occasionally experienced pain and a burning sensation during urination, as well as occasional pain in my abdomen and lower back.
I went to the hospital for an examination, and the doctor arranged for a urinalysis (without bacterial culture).
The results showed normal white blood cell counts, so the doctor did not prescribe antibiotics.
Instead, I was given two medications: oxybutynin for overactive bladder and alfuzosin for benign prostatic hyperplasia.
I have researched this, and pain and burning during urination are almost always associated with urethritis or cystitis.
Is it really unnecessary to treat with antibiotics?

Rui, 40~49 year old female. Ask Date: 2016/12/05

Dr. Du Shixi reply Urology


Hello: If the urine test results are normal, there is no need to use antibiotics.
Please ensure you get enough sleep, drink plenty of water, avoid spicy and irritating foods, and refrain from alcohol.
Engaging in moderate daily exercise (such as walking) may help improve your condition.
If you have followed these recommendations and do not see any improvement after three days, please return for a follow-up examination.
Thank you for your inquiry.

Reply Date: 2016/12/05

More Info


Understanding bladder overactivity and the appropriate treatment options can be quite complex, especially when symptoms such as pain and burning during urination arise. In your case, it appears that you have experienced discomfort in urination, along with abdominal and lower back pain. After a visit to the hospital, your urine was tested, and the results indicated a normal white blood cell count, leading your doctor to refrain from prescribing antibiotics. Instead, they prescribed oxybutynin for bladder overactivity and alfuzosin for prostate enlargement.

To address your concerns, it is essential to understand the underlying reasons for your symptoms and the rationale behind your doctor's treatment plan.
1. Urinary Symptoms and Infections: Painful urination and a burning sensation are indeed common symptoms associated with urinary tract infections (UTIs), including cystitis (bladder infection) or urethritis (inflammation of the urethra). However, the presence of white blood cells in the urine is a critical indicator of infection. In your case, a normal white blood cell count suggests that there is no significant infection present. This is a key factor in determining whether antibiotics are necessary.

2. Bladder Overactivity: Oxybutynin is an anticholinergic medication that helps manage symptoms of overactive bladder, which can include urgency, frequency, and in some cases, discomfort during urination. It works by relaxing the bladder muscle, thereby reducing the urge to urinate and alleviating discomfort. This medication is particularly useful when the symptoms are not due to an active infection but rather due to bladder hyperactivity.

3. Prostate Health: Alfuzosin is an alpha-blocker that is often prescribed for men with benign prostatic hyperplasia (BPH), which can contribute to urinary symptoms such as difficulty urinating or discomfort. By relaxing the muscles in the prostate and bladder neck, alfuzosin can help improve urine flow and reduce discomfort.

4. When Antibiotics Are Not Needed: In cases where there is no evidence of a bacterial infection, as indicated by your urine test, antibiotics would not be beneficial and could potentially lead to unnecessary side effects or antibiotic resistance. It is crucial to avoid overprescribing antibiotics, as this can contribute to the growing issue of antibiotic resistance.

5. Other Considerations: If your symptoms persist or worsen despite treatment, it may be necessary to conduct further evaluations. This could include additional urine tests, imaging studies, or even a referral to a urologist for specialized care. Conditions such as interstitial cystitis or other bladder-related disorders could also be considered if standard treatments do not yield improvement.

In conclusion, your doctor’s decision to avoid antibiotics was based on the absence of an infection as indicated by your urine test results. The prescribed medications aim to address bladder overactivity and prostate health, which may be contributing to your symptoms. It is essential to follow up with your healthcare provider if your symptoms do not improve or if you have any new concerns. Always communicate openly with your doctor about your symptoms and any changes you experience, as this will help guide your treatment effectively.

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