Can Liver Tumors Progress to Liver Cancer? Your Risks - Gastroenterology and Hepatology

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Can a liver tumor transform into liver cancer?


Hello, doctor! In September of this year, I went for a check-up due to gastrointestinal discomfort, and an abdominal ultrasound detected a 0.6 cm tumor on my right liver.
During a follow-up visit in December, it had increased to 0.8 cm.
The doctor mentioned that it could be a matter of angle.
Blood tests for hepatitis A, hepatitis B, and tumor markers all came back normal, and I was advised to continue monitoring.
I would like to ask the doctor if there is a possibility of deterioration? Could it turn into liver cancer? (There is no family history of liver cancer.) Can I safely prepare for pregnancy?

Xiao Mei, 30~39 year old female. Ask Date: 2016/12/08

Dr. Chen Shidian reply Gastroenterology and Hepatology


Hello, Miss.
Please do not worry; the chances are likely low.
Just continue to monitor any changes in size.
Changhua Hospital cares about your health.
Chen Shidian.

Reply Date: 2016/12/08

More Info


Liver tumors can indeed progress to liver cancer, particularly in the context of underlying liver disease such as cirrhosis or chronic hepatitis. In your case, the presence of a 0.6 cm tumor that has grown to 0.8 cm over a few months warrants careful monitoring, even if initial blood tests for hepatitis A, B, and tumor markers were normal.
The risk of a benign liver tumor transforming into a malignant one depends on several factors, including the type of tumor, its size, and the overall health of the liver. Common benign liver tumors include hemangiomas and focal nodular hyperplasia, which typically do not progress to cancer. However, hepatocellular adenomas, particularly in women taking oral contraceptives or those with underlying liver disease, can have a risk of malignant transformation.
In your case, the growth of the tumor, albeit small, is a signal that should not be ignored. While the increase in size could be due to benign factors such as imaging angle or technique, it is essential to maintain a proactive approach. Regular follow-up with imaging studies, such as ultrasound or MRI, is crucial to assess the tumor's characteristics over time. If the tumor continues to grow or changes in appearance, further evaluation, including a biopsy, may be necessary to rule out malignancy.

Regarding your concerns about pregnancy, it is generally advisable to ensure that any potential health risks are adequately managed before conception. If the tumor is benign and there are no other liver health issues, you may be able to proceed with pregnancy. However, it is essential to consult with your healthcare provider, who can assess your overall health, the nature of the tumor, and any potential risks associated with pregnancy.

In summary, while the risk of your liver tumor progressing to cancer cannot be completely ruled out, the current evidence suggests that careful monitoring is the best course of action. Regular follow-ups and imaging will help ensure that any changes are detected early. Always discuss your concerns and plans with your healthcare provider to make informed decisions about your health and future pregnancy.

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