Cervical Cancer Treatment Options for Stage 3B Patients - Oncology

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Cervical cancer treatment


The patient is a 72-year-old mother who has been diagnosed with stage 3B cervical cancer.
The gynecologist believes that surgery is not advisable.
After undergoing 28 sessions of radiation therapy and 3 sessions of chemotherapy, the tumor has slightly shrunk but still remains.
The hematologist has suggested performing a PET scan to confirm whether there is metastasis before deciding on the treatment approach.

The current inquiry is whether, since radiation therapy has been completed and cannot be repeated, the only options left are chemotherapy and surgery.
If she goes directly to a large metropolitan hospital for treatment, will the chemotherapy agents be of better quality, or will they be similar? Regarding the decision of whether to proceed with surgery, should she seek a second opinion from a physician at a metropolitan medical center, or should she complete the PET scan at the original hospital before deciding on the treatment plan? Thank you.

hdjdjfkkd, 40~49 year old female. Ask Date: 2016/12/09

Dr. Lai Yicheng reply Oncology


Dear Mr.
HDJDJKFKD,
Thank you for your letter.
Here are my responses:
1.
After 28 sessions of radiation therapy and 3 sessions of chemotherapy, a PET scan is required.
It is important to rest for 6 to 8 weeks to avoid false positives.
2.
The effectiveness of the treatment will be confirmed after the PET scan.
If the results are favorable, you can continue with the current radiation therapy and chemotherapy.
There is a strong consensus regarding the current treatment plan, and it is best to trust your physician.
3.
The choice of medication will not differ between large and small hospitals.
It should be based on the consensus between the physician and the family.
Thank you for your inquiry.

Best regards,
Dr.
Lai Yi-Cheng
Department of Radiation Oncology
Changhua Hospital

Reply Date: 2016/12/09

More Info


When dealing with a diagnosis of Stage 3B cervical cancer, especially in an elderly patient like your 72-year-old mother, it is crucial to understand the treatment options available and the implications of each choice. Stage 3B cervical cancer indicates that the cancer has spread to the lower third of the vagina and/or has spread to the pelvic wall, but it has not spread to distant organs. This stage is often associated with more advanced disease, and treatment typically involves a combination of therapies rather than surgery alone.

In your mother's case, the initial recommendation against surgery was likely due to the size of the tumor and its advanced stage. Surgical intervention in Stage 3B cervical cancer is generally not the first line of treatment because the risks may outweigh the benefits, especially considering the potential for significant complications and the patient's overall health status. Instead, the standard treatment for this stage often includes radiation therapy combined with chemotherapy, which is known as chemoradiation. This approach aims to shrink the tumor and control the disease.

Since your mother has already undergone 28 sessions of radiation therapy and three cycles of chemotherapy, it is essential to evaluate the effectiveness of this treatment. The fact that the tumor has slightly shrunk is a positive sign, but the persistence of the tumor indicates that further treatment may be necessary. The hematologist's suggestion to perform a PET scan is a prudent step, as it will help determine if there is any metastasis (spread of cancer) to other areas of the body. This information is vital for deciding the next steps in treatment.

Regarding your question about whether to seek treatment at a larger urban medical center, it is generally advisable to obtain a second opinion, especially in complex cases like this. Larger hospitals often have access to more advanced treatment options, clinical trials, and specialists who may have more experience with Stage 3B cervical cancer. However, the chemotherapy agents used in treatment may not differ significantly between hospitals; rather, the expertise of the medical team and the availability of supportive care can vary.

If surgery is being considered again, it is essential to have a thorough discussion with the healthcare team about the potential benefits and risks. In many cases, surgery may not be the most effective option for Stage 3B cervical cancer, and the focus may remain on systemic therapies like chemotherapy.
In summary, it is crucial to have open discussions with your mother's healthcare providers about her treatment options, the results of the upcoming PET scan, and the potential for further chemotherapy or clinical trials. Seeking a second opinion at a larger medical center can provide additional insights and options. Ultimately, the goal is to ensure the best possible quality of life and treatment outcomes for your mother.

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