False Positives in Urology: The Case of Cauliflower Lesions - Urology

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Cauliflower examination issues?


Dear Doctor: Is it possible to test positive for an infection without any visible lesions related to genital warts? I carefully observe my penis every day and see no abnormalities, and I have pearly penile papules, which do not appear different.
However, my first test was negative, and the report indicated a staphylococcal infection.
A week later, the test became positive for type six.
I am currently undergoing viral load testing to guide treatment, but during the waiting period for the report, should I start treatment or wait for the results? Is there anything else I need to be aware of? Thank you.

danxin, 20~29 year old female. Ask Date: 2016/12/19

Dr. Du Shixi reply Urology


Hello: Even if you test positive, there may be no lesions to address, which is the clinical challenge.
It would be advisable for you to visit the urology department at the hospital for further evaluation.

Reply Date: 2016/12/19

More Info


Understanding false positives in urology, especially in the context of cauliflower lesions, is crucial for accurate diagnosis and treatment. Cauliflower lesions, often associated with conditions such as genital warts caused by human papillomavirus (HPV), can sometimes lead to confusion in diagnostic testing, particularly when it comes to identifying infections.

In your case, it appears that you have undergone testing for a staphylococcal infection, which initially returned negative but later became positive. This fluctuation in test results can occur for several reasons. For instance, the presence of certain skin flora, like staphylococci, can sometimes be misinterpreted as an infection, especially if the sample was contaminated or if the bacteria were present in low quantities. Additionally, the immune response can vary, leading to different results over time.

Regarding your concern about whether cauliflower lesions can exist without an underlying infection, the answer is yes. Cauliflower-like growths can be benign and may not necessarily indicate an active infection. However, they can also be indicative of viral infections, such as HPV, which may require monitoring or treatment depending on their characteristics and associated symptoms.

As for your current situation, where you are awaiting results from a viral load test, it is generally advisable to consult with your healthcare provider regarding whether to initiate treatment immediately or wait for the results. If you are experiencing symptoms such as discomfort, pain, or significant anxiety about the lesions, your doctor may recommend starting treatment to alleviate these concerns. On the other hand, if the lesions are asymptomatic and you are not at high risk for complications, your doctor might suggest waiting for the test results before proceeding with treatment.

In the meantime, it is essential to maintain good hygiene and avoid any activities that could exacerbate the condition, such as sexual intercourse, until you have a clearer understanding of your diagnosis. Additionally, keep monitoring for any changes in the lesions or new symptoms, and report these to your healthcare provider promptly.

Lastly, it is crucial to have open communication with your healthcare provider about your concerns and the implications of your test results. They can provide you with the most accurate information tailored to your specific situation, including whether further testing or treatment is necessary.

In summary, while cauliflower lesions can sometimes be benign, the presence of an infection cannot be ruled out without appropriate testing. Your fluctuating test results highlight the importance of follow-up and possibly further investigation. Always consult your healthcare provider for personalized advice and treatment options based on your unique circumstances.

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