Impact of Xanax and Fever on Fetal Development During Pregnancy

Ingested Xanax (a Category D medication) at fourteen weeks of pregnancy?

I had a fever when I was fourteen weeks pregnant and went to the clinic for an IV to reduce the fever.
The doctor prescribed me Zannano (a Category D medication), and I took a total of one pill.
Will this affect the fetus? Additionally, I would like to know if having a fever (38 degrees Celsius) can impact the fetus.
Thank you.

Ru Ru, 30~39 year old female. Ask Date: 2017/01/19

Dr. Zhang Kunmin reply Obstetrics and Gynecology

Hello, the use of Xanax during early pregnancy should be evaluated by a physician.
If there is a fever, the cause must be investigated to determine if it could affect the fetus.
Thank you! Wishing you safety and health.
Dr.
Chang.

Reply Date: 2017/01/19

More Info

The use of Xanax (alprazolam) during pregnancy, particularly in the first trimester, raises significant concerns regarding fetal development. Xanax is classified as a Category D medication by the FDA, which indicates that there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans. This classification suggests that while the drug may be necessary for certain medical conditions, its use during pregnancy should be approached with caution and under strict medical supervision.

When considering the impact of Xanax on fetal development, it is important to note that studies have shown a potential association between the use of benzodiazepines, including Xanax, and various adverse outcomes. These may include an increased risk of congenital malformations, particularly when used in the first trimester when the fetal organs are developing. Additionally, there is a risk of withdrawal symptoms in newborns if the mother has been using the medication regularly during pregnancy.

In your case, you mentioned that you took Xanax for fever treatment at 14 weeks of pregnancy. Since you only took one dose, the immediate risk may be lower compared to long-term use; however, it is still advisable to discuss this with your healthcare provider. They can evaluate your specific situation, including the timing of the dose and any other factors that may influence fetal health.

Regarding fever during pregnancy, a temperature of 38 degrees Celsius (100.4 degrees Fahrenheit) can be concerning, especially in the first trimester. Elevated maternal body temperature during early pregnancy has been associated with an increased risk of neural tube defects and other developmental issues. It is crucial to identify the underlying cause of the fever and manage it appropriately. In general, mild fevers can often be treated with acetaminophen, which is considered safer during pregnancy than other medications.

In summary, while a single dose of Xanax may not pose a significant risk, it is essential to consult with your obstetrician or healthcare provider to discuss any potential implications for your pregnancy. They may recommend additional monitoring or assessments to ensure the health of both you and your baby. Additionally, if you experience fever, it is vital to address the cause and manage it effectively to minimize any potential risks to fetal development. Always prioritize open communication with your healthcare team regarding any medications or symptoms you experience during pregnancy.

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